William Harvey

CHAPTER IX.

Chapter 124,872 wordsPublic domain

Brooks, W. K., "William Harvey as an Embryologist," _Johns Hopkins Hospital Bulletin_, vol. viii., p. 167.

Harvey's Notes on Galen, _The Athenæum_, October, 1888, No. 3180, p. 452.

INDEX

A

Alston, Dr., 157

Ameius Gulielmus, 18

Anatomical demonstrations, 41-46; method of conducting, 57-60; lectures, cost of, 45, 46; teaching of Reid compared with that of Harvey, 232-237; works of Harvey, 188

Anatomy, early teaching of, 39; study of, at Cambridge, 13; value of comparative, 201

Andrewes, Dr., 88, 90, 91, 97, 98, 104, 232

Andrich, Dr., 18, 27

Anecdotes of Eliab Harvey, 8; William Harvey, 144-145; Sir Charles Scarborough, 142

Appearance of Harvey, 52

Apothecaries' opinions of Harvey's prescriptions, 74; visitations of, 75-79

Aristotle, capillamenta of, 213; Harvey's opinion of, 68, 72

Armorial bearings of the Harvey family, 2

Art, Harvey an authority on, 115

Arteries, course of blood in, 213

Artistarum universitas, 16, 27

Arundel, Earl of, 111

Aubrey's first recollection of Harvey, 130; Harvey's advice to, 146

Auricle, movement of, 200

Autograph of Harvey in de Glarges' album, 123

Aveling, Dr., 83

Aylesford, Earls of, their relationship to Harvey, 7

B

Bacon and Harvey, 71

Barber Surgeons Company, abortive attempt to found a surgical lectureship, 46; anatomical teaching at, 39, 40-44, 57-60; Reid's lectures at, 47, 231; Dr. Scarborough's lectures at, 142

Barnacle goose, account of, 93, _note_

Bartholomew's Hospital, _see_ St. Bartholomew's Hospital

Bass rock, description of, 93

Bathurst, George, 130

Bethune, Dr., 83, 118

Birthplace of William Harvey, 4

Bleeding, proof of the circulation from the operation of, 214, 216

Blood, circulation of, as described in Lumleian lectures, 65

Blood, quantity of, 208

Brent, Sir Nathaniel, 134, 138, 139

Breviarium Bartholomei, 215

Broderield, the, 11

Browne, Dr. Lancelot, 29

Burmarsh, Harvey's estate at, 163

Butchers proof of the circulation, 210

C

Caius College, Cambridge, Harvey entered at, 12

Caius, Dr., 13, 15

Caldwall, Dr., 46, 47, 48

Calidum innatum, 192, 255

Cambridge, anatomy at, 13; graduation of Harvey at, 14, 27; Harvey matriculated at, 12, 21

Canons, Harvey's lecture, 62-64

Capillamenta of Aristotle, 213

Cassowary, Harvey's account of, 239

Censors of the College of Physicians, their duties, 75, 76

Centennial eggs, 240

Cesalpino, 213, 217

Chambers, Dr., 83

Charge of the Physician at St. Bartholomew's Hospital, 35

Charles I., escape of, from Oxford, 138; Harvey appointed physician to, 70; Harvey's friendship with, 240-246; interest of, in the pursuits of Harvey, 240-46

Chick heard in shell, 198, 251; reasons for the escape of from the egg, 250-254

"Christianismi Restitutio," 207

Circulation of the blood, account of, 199-202; anatomical proof of, 206, 219; butcher's proof of, 210; comparative anatomy of, 222; deduced from syncope, 210, 218; disquisition to Riolanus on, 224; formulation of theory of, 206; Harvey's account of, 190; Harvey's propositions about, 207; mathematical proof of, 208; proof of, 206; proof of from amount of milk secreted, 211; proof by demonstration, 221, 67; by continuous flow in, 217; mathematical, 208; from phlebotomy, 214, 216; from surgical operation, 214; theory of enunciated in Lumleian lectures, 65

Circulator, meaning of term, 74

Civil war, 117-140

Clarke, John, Dr., 104

Clavis Mathematica, 161

Cold blooded animals, heart's movements in, 195

College of Physicians, anatomical teaching in, 39; attend the funeral of Harvey, 167; Harvey admitted a member, 29; admitted a Fellow, 31; Harvey's bequests to, 163, 182; Harvey's gifts to, 154-156; Harvey elected censor, 75; erect a statue to Harvey, 155; Harvey's pointer at, 57, _note_; Harvey portraits at, 10; leave of absence granted to Harvey, 81; library rules, 86; Lumleian lectures at, 45-50; offices held by Harvey, 51, 75, 80, 157, 158; portraits of the Harvey family at, 10; sites of, 50, 51; tanned skin presented to, 103; translation of Harvey's remains by, 173

Columbus Realdus, 207

Combe, near Croydon, 7

Comparative anatomy of the circulation, 222; destruction of Harvey's notes on, 125, 262; value of, 202

Concilarius, duties of, 16; Harvey elected at Padua, 18

Cookæus, Joh., 17

Contemporary estimate of Harvey, 225

Court physician, 70

Criticism, contemporary of Harvey, 225

Croydon, 7

Cusa, Cardinal Nicholas de, 215, _note_

Cusanus, 215, _note_

D

Darcy, Sir Robert, the case of, 228

Darwin, Prof. George, 19, 20

Davies, Dr., 51

Death mask of Harvey, 167, 175

Demonstration, anatomical method of conducting, 57-61; of Anatomy, 42-47; of the circulation, 221

Derby, Dr. Harvey at, 126

Destruction of Harvey's papers, 125, 262

Development, treatise on, 89, 238-263; introduction to, 147-154

Diastole, meaning of the term, 193, _note_

Diploma, of Harvey, 26

Dunne, William, 51

E

Eccentricities of Harvey, 144, 145

Edgehill, Harvey at, 126

Eggs, centennial, 240

Elect, Harvey chosen, 80; duties of, 80

English nation at Padua, 18

Ent, Dr., 182; account of Harvey, 146-153; meets Harvey at Rome, 115

Epitaph of Joan Harvey, 5

Estey, George, 11

Euclid, Scarborough the first English editor of, 139

F

Fabricius Hieronymus, 15, 23, 219; lectures of, 23; honours paid to, 23; relation of to Harvey, 25, 240, 249-254; theatre of, 23

Fainting, assigned cause of, 214; proof of circulation deduced from, 211, 218

Ferraris, Prof. Carlo, 18, 19

Finch, Sir H., 7

Floyer, Sir John, 215, _note_

Folkestone, 3, 5, 11

Footman, the King's, 5

Forster, Richard, 51

Fracastorius' opinion of the heart's movement, 193

France, Harvey in, 84

G

Generation, account of treatise on, 238-263; introduction to, 147-154; treatise on, 89

Gerarde's "Herbal" quoted, 93, _note_

Germany, Harvey's travels in, 123

Girardi, Dr., 18

Glarges, Philip de, 123

Glove, Harvey's experiment with, 196

Gonville Hall, 13

Goose, solan or barnacle account of, 93, _note_

Gurgany, John, 137

Guestling, the, 12

H

Halke, Joane, 3

Halke, Thomas, 3

Hamey, Dr., 157

Harvey, Amye, 9

Harvey, Aubrey's description of William, 52

Harvey, mortuary chapel, the, 8, 168

Harvey, Daniel, 6, 143

Harvey, Eliab, 7, 38, 143, 166, 168, 177, 182

Harvey, Sir Eliab, G.C.B., anecdote of, 8

Harvey, Elizabeth, 29-31

Harvey, Joan, 3-5

Harvey, John, 5, 30, 33, 141

Harvey, Matthew, 9, 141

Harvey, Michael, 9, 141

Harvey, Mrs., 29-31, 141

Harvey, Sarah, 5

Harvey, Thomas, 3-5, 6, 11, 29

Harvey, Walter, 1

Harvey, Dr. William, advice to Aubrey, 146; anatomical teaching compared with that of Reid, 231-237; anatomical works of, 188-237; an art collector, 115; and Hofmann, 113; and Sir Charles Scarborough, 109, 139, 140, 142; and the Civil War, 117-140; and the English school of Anatomy, 134; and Willoughby, 126; anecdotes of, 144-146; apothecaries' opinion of, 74; appearance of, 52; armorial bearings of, 2; as a literary man, 159; at Cambridge, 12, 27; at Padua, 14-27; at Padua, elected councillor, 19

Harvey, Dr. William, at College of Physicians, censor, 75; demonstrator's rod at, 57, _note_; Elect, 80; elected candidate, 29; elected Fellow, 31; elected Concilarius, 158; elected President, 157; leave of absence granted to, 82; Lumleian lecturer, 51; Lumleian lectures, notes of, 53-56, 62-69; rules for library drawn up by, 87; Tabulæ Harveianæ, 68; Treasurer, 80

Harvey, William, Dr., at Court, accompanies King to Scotland, 92; Physician in Ordinary to King Charles I., 70, 87-88; relation to the King, 89; Physician Extraordinary to King James I., 70; Senior Physician in Ordinary, 118; at Oxford, 126-140; Letters to Prince Rupert, 130, 131

Harvey, Dr. William, at Ratisbon, 115; at Rome, 115; at St. Bartholomew's Hospital, elected physician in reversion, 32; last payment to, 132, 133; retirement from, 132, 133; leave of absence granted to, 82; physician to, 34-38; rules for the government of, 96; stipend as physician, 38; substitute appointed for, 90; at Trinity College, Oxford, 130; attends Prince Maurice, 131; autograph in de Glarges' album, 123; autopsy on old Parr, 111; birthplace of, 4; builds library and museum at College of Physicians, 154-157; burial of, 167; candidate at the College of Physicians, 29; compared with John Hunter, 184-187; complains of old age, 159; contemporary criticism of, 225; estimate of, 184-187; death of, 166; death mask of, 167, 175; debt to Fabricius, 24, 25; demonstrator's rod at the College of Physicians, 57, _note_; destruction of his manuscripts, 124, 262; diploma of, 26; dissections by, 66; early life of, 11-13; eccentricities of, 144, 145, 146; elected consiliarius at Padua, 18; elected President of College of Physicians, 157; elected Warden of Merton, 135; Ent's account of, 146-157; entries concerning, at Padua, 18, 27; eulogy of, 184-187; experiments on himself, 255; Fellow of the College of Physicians, 31; friendship of Charles I. with, 240-247; graduates M.D., at Cambridge, 27; at Oxford, 130; at Padua, 26; Howell's letter to, 160; humour of, 30, 64, 68, 69; ill practice by, 110; in London, 28, 31; jargon used by, 56; knowledge of Latin, 14, 18; Lancashire witches, 104-109; later years of, 141; lecture canons of, 62-64; letters to Prince Rupert, 130, 131; liberality of, 24, 38, 86, 154; lineage of, 1; love for Virgil, 54; marriage of, 29; meets Dr. Ent at Rome, 115; midwifery, practical knowledge of, possessed by, 110; muscular lecture, 67; mystical side of, 255; notes of muscular lecture, 67-69; notes of visceral lecture, 53-56; opinion of Aristotle, 68; pathological knowledge of, 228; pathological observations of, 228, 246; peculiarities of, 144, 145, 146; personal appearance of, 52; physiological advances since the time of, 237, 238; pillage of his lodgings, 124, 262; powers of observation of, 247-254; practice of, 71-75; probate of will of, 184; publication of his work, "De motu sanguinis," 73; religion of, 55, 187; 256-260; remains, treatment of, 170-175; rules drawn up by, 87; treatise on development by, 238-242; estimate of treatise on Generation, 261; resigns the Lumleian Lectureship, 163; similes used by, 68, 69; speech at Merton College, 135; "stemma" of, 19, 20; stipend as Court Physician, 88, 118-121; as Physician to St. Bartholomew's Hospital, 38; sues Lumleian trustees, 122; surgery as well as medicine practised by, 109; translation of remains, 170-175; travels with the Earl of Arundel, 112; travels with the Duke of Lennox, 81-87; travels with King Charles, 90; treatise on development, 89; will of, 176-184

Hawke, Joane, 3

Hawke, Thomas, 3

Heat, innate, 255

Heart and lungs, connection of, 201

Heart, mechanism of contraction, 196

Heart's movements, experiments concerning, 195; in cold blooded animals, 194, 197; Fracastorius' opinions of, 193; simile for, 200; relation of lungs to, 223; Reid's knowledge of, 232-236 Heberden, Dr., 144 Hempstead, Harvey's burial at, 168, 169, 170, 175; mortuary chapel at, 8 Henry III., death of, 1 Hervey, Sir Walter, 1 Henrietta Maria, Queen, at Merton College, 136 Hofmann and Harvey, 113 Hollar's anecdote of Harvey, 114 Holsbosch, Dr., bequest of, 87 Horst, Dr., 159 Hospital, _see_ St. Bartholomew's Hospital Howell's letter to Harvey, 160 Humidum primigenium, 256, 261 Hunter, John, compared with Harvey, 184-187

I

Identification of students in Italy, 17

Innate Heat, 255

Insects, destruction of Harvey's notes on, 125; heart in, 198

Italian Universities, 14-16

Italy, identification of students in, 17

J

James I., Harvey appointed physician to, 70

Jargon used by Harvey in his notes, 56

Jenkin, Juliana, 3

Jenkin, William, 3

Juristarum, universitas, 16, 17

K

King's footman, 5

King's turnspit, 6

L

Lancashire Witches, story of, 104-109

Lecture, anatomical importance of, 58

Lectures, Lumleian, 39-69

Lectures, notes of Harvey's Lumleian, 53-69

Lennox, Duke of, 81

Library, rules for use of, 87

Linacre, 50

Lineage of Harvey, 1

Listerus, Josephus, 17, 26

Literature, Harvey's love for, 160

Lock Hospitals, 99, _note_

London, Harvey settles in, 28, 31

Lumley, Lord, 47

Lumley, Lord, heirs of, sued by Harvey, 122

Lumleian lecturer, Harvey appointed, 51

Lumleian lectures, 39-69

Lumleian lecturers, early, 51

Lumleian lectures, foundation of, 46, 47

Lumleian lectures, schemes of, 48-50

Lumleian lectureship resigned by Harvey, 163

Lumleian trustees sued by Harvey, 122

Lungs, circulation in, 204

Lungs and heart, connection of, 201

Lungs, relation of heart to, 223

Lungs, use of, 204

M

Magistral universities, 16

Mantuan war, Harvey's description of the results of, 85

Marriage of Harvey, 29

Mathematical proof of circulation, 208

Matriculation, Harvey's, at Cambridge, 12; at Padua, 17

Maurice, Prince, 131, 138

Merton College, Harvey at, 134-140; marriages at, during royalist occupation, 137; Queen Henrietta at, 136

Micklethwaite, Sir John, 133

Midwifery, practical knowledge of, possessed by Harvey, 110, 126

Milk, proof of circulation from secretion of, 211

Mirfield, John of, 216

Moesler, Dr. Adam, 83

Moore, Dr. Norman, 36, 53, 215, 262

Moisture the primigenial, 256, 261

Muscular lecture, 67

N

Nardi, Dr., 160, 161

Nottingham, the first Earl of, 7

Nuremberg, Harvey at, 113

O

O'Birne, Mr., anecdote of, 8

Observation, Harvey's powers of, 247

Oxford, surrender of, 138

Oxford, Harvey at, 126-140

Oughtred's "Clavis Mathematica," 162

Old Parr, 111

P

Padua, celebration at, 19; diploma granted to Harvey, 26; election of rector at, 21; entries concerning Harvey at, 18, 27; nations at, 18; the Universities at, 14-27

Padua University, life at, 21-23; why selected by Harvey, 15

Paget, Sir George, 69, 242

Paget, Sir James, 5

Parr, Old, 111

Paris, Harvey in, 84

Parrot, Mrs. Harvey's, 30

Pathological observations by Harvey, 227, 245

Pepperer, Walter Harvey a, 1

Pepys, Mr., attends an anatomical lecture, 44

Perfusion experiment, 197

Perquisites of Court Physicians, 118-119, 121

Phlebotomy, proofs of the circulation from, 214, 216

Physicians, College of, _see_ College of Physicians

Physicians, their relation to Surgeons, 100, 101

Physiological advances since the time of Harvey, 236

Pigeon, experiment with heart of, 197

Pillage of Harvey's lodgings, 124, 262

Portraits of the Harvey family, 10

Prayers used to measure time, 216

Prescriptions, secrecy attaching to, 102, 103

Primrose, James, 80

Primrose, Serjeant-Surgeon, 83

Probate of Harvey's will,184

Prujean, Dr., 154, 156, 157,158

Pulmonary circulation, 204

Pulse watch, 215, _note_

R

Ratisbon, Harvey at, 115

Rector of Italian University, honours paid to, 23

Rector of Italian University, election of, 21

Reid, Alexander, 47, 57, 231, 237

Religion of Harvey, 55, 187

Richardson, Sir Benj. Ward, 170

Riolanus, treatise to, 224-230

Roehampton, 5, 7, 166

Rolls Park, 4, 10

Rolls Park portraits, 10

Rome, Harvey at, 115

Rupert, Prince, 130, 131, 138

Royal College of Physicians, _see_ Physicians, College of

S

St. Bartholomew's Hospital charge to the physician, 35; duties of physician, 34-38; Harvey appointed physician, 34; Harvey appointed physician in reversion, 32; physician's lodgings at, 37; rules for governance of, 96, 99-103

St. Sepulchre's, Harvey married at, 29

Scarborough, Sir Charles, 44, 52, 109, 122, 139, 140, 142, 162, 182

Scotland, Harvey in, 92

Scotch nation at Padua, 18

Screopeus, Hen., 17

Scrope, Adrian, treated by Harvey, 127

Servetus, 207

Shakespeare's death, 62

Shrimps, heart in, 198

Sieveking, Sir E. H., 53

Silvius, Jacques, 24

Skin, human, presented to College of Physicians, 103

Skull, human, at Sidney Sussex College, Cambridge, 244

Slegel, Dr., letter to, 230

Smith, Capt., at Edgehill, 129

Smith, Dr. Edward, 82, 90, 91, 92, 130, 131, 156

Solan goose, account of, 93, _note_

Spider, experiment with poison of, 255

"Stemma" of Harvey at Padua, 19, 20

Stipend of Court Physician, 88, 118, 119, 121; of physician to St. Bartholomew's Hospital, 38

Student Universities, 16

Students, identification of, in Italy, 17

Surgical Lectureship founded at the Royal College of Physicians, 48

Surgeons subordinate to physicians, 100-102

Surgery practised by Harvey, 109; proof of circulation from, 214

Syllabus of Lumleian lectures, 49

Syncope, assigned cause of, 214

Systole, meaning of the term, 193, _note_

T

Tabulæ Harveianæ, 66

Tearne, Dr., 44

Theatre of Fabricius at Padua, 23

Thirty Years' War, account of devastation by, 114

Tight lacing, Harvey's treatment for, 65

Time, measurement of, 215

Turnspit, the King's, 6

Trinity College, Oxford, Harvey at, 130

U

Universitas artistarum, 16, 27

Universitas juristarum, 16, 21, 27

University of Cambridge, Harvey graduates at, 14, 27; Harvey matriculated at, 12

Universities of Italy, 14

University of Oxford, 129-140

University life at Padua, 14-27

Universities, types of, 16

V

Valves in veins, their discovery, 24

Valves, uses of in veins, 219, 220

Veins, course of the blood in, 213; uses of valves in, 219, 220; valves of, their discovery, 24

Ventricles, movements of, 199

Verney, Sir Edward, 128

Viewing patients, the practice of, 111

Visitation of Apothecaries' shops, 75-79

Virgil, Harvey's love for, 54

Vlackveld, Dr., Harvey's letter to, 163

W

Walpole's anecdote of Eliab Harvey, 8

Ward, Samuel, Master of Sidney Sussex College, 243

Ward, Seth, 162

Watch for the pulse, 215

Wilkenson, Dr., 34

Will of Harvey, 176

Willoughby, Dr. Percival, 126

Winchelsea and Aylesford, Earls of, their relationship to the Harvey family, 7

Witches, Lancashire, story of, 104

Wood, Anthony, 138, 142

Y

York, Duke of, 127, 138

Z

Zadig, method of, 248

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FOOTNOTES:

[1] The usual contraction for Magister, indicating his university degree of Artium Magister or M.A.

[2] The College of Physicians still possess a little whalebone rod tipped with silver which Harvey is said to have used in demonstrating his Lumleian lectures.

[3] P. 54.

[4] The reference is to the passage in Gerarde's "Herbal," giving an account of the miraculous origin of the Solan Goose. It runs: "But what our eyes have seen and hands have touched we shall declare. There is a small island in Lancashire called the Pile of Foulders, wherein are found the broken pieces of old and bruised ships, some whereof have been cast thither by shipwreck, and also the trunks and bodies with the branches of old and rotten trees cast up there likewise, whereon is found a certain spume or froth that in time breedeth unto certain shells, in shape like those of a mussel, but sharper pointed, and of a whitish colour wherein is contained in form like a lace of silk finely woven as it were together, of a whitish colour, one end whereof is fastened unto the inside of the shell, even as the fish of oysters and mussels are; the other end is made fast to the belly of a rude mass or lump, which in time cometh to the shape and form of a Bird; when it is perfectly formed the shell gapeth open, and the first thing that appeareth is the aforesaid lace or string; next come the legs of the bird hanging out, and as it groweth greater it openeth the shell by degrees till at length it is all come forth and hangeth only by the bill; in short space after it cometh to full maturity and falleth into the sea, where it gathereth feathers and groweth to a fowl bigger than a mallard and lesser than a goose, having black legs and bill or beak, and feathers black and white, spotted in such manner as is our Magpie... which the people of Lancashire call by no other name than a tree goose; which place aforesaid and all those parts adjoining do so much abound therewith, that one of the best is bought for threepence. For the truth hereof if any doubt, may it please them to repair unto me, and I shall satisfy them by the testimony of good witnesses" (Gerarde's "Herbal," A.D. 1636, p. 1588, chap. 171. "Of the Goose Tree, Barnacle Tree, or the Tree-bearing Goose").

A solan goose was looked upon for many years as a delicacy. Pennant states that about the middle of the seventeenth century a young one was sold for 20_d._ He also quotes the following newspaper cutting:--"SOLAN GOOSE.--There is to be sold by John Walton, Jun., at his stand at the Poultry, Edinburgh, all lawful days in the week, wind and weather serving, good and fresh solan geese. Any who have occasion for the same, may have them at reasonable rates.--Aug. 5, 1768."

[5] The outhouses, Sir James Paget tells us, were the Lock Hospitals belonging to St. Bartholomew's Hospital. There were two outhouses, one in Kent Street, Southwark, the other in Kingsland. They were founded originally as Lazar-houses for the use of lepers. The "Lock" in the Borough was used for women; the "Spital" in Kingsland for men. Each contained about thirty beds and was under the charge of a guider, guide or surgeon, who was appointed by the Governors of the Hospital, and received from them in Harvey's time an annual stipend of four pounds a year and fourpence a day for the diet of each patient under their care.

[6] This and the two following regulations illustrate in a very remarkable manner the complete subjection in which the physicians held the surgeons in Harvey's time and for many subsequent years. It was not until Abernethy was surgeon to the hospital, at the beginning of the century, that the surgeons were allowed to prescribe more than a black draught or blue pill for their patients until the prescription had been countersigned by one of the physicians.

[7] And no wonder, for it meant that their prescriptions were to be made public, whilst those of the Physician were kept secret [sec. 16], and at this time every practitioner had some secret remedy in which he put especial trust.

[8] The kindness of Dr. Norman Moore enables me to reproduce a facsimile of Harvey's handwriting taken from his "muscular lecture." The block appeared originally in the _Lancet_, vol. i., 1895, p. 136.

[9] Perhaps the Essay on the Circulation of the Blood addressed to Riolanus, published at Cambridge in 1649.

[10] The _systole_ of the heart means its contraction: the _diastole_ of the heart means its dilatation.

[11] Cardinal Nicholas de Cusa [Cusanus] is said to have counted the pulse by a clock about the middle of the sixteenth century, but Dr. Norman Moore points out to me that in reality he counted the water-clock, then in use, by the pulse. The number of pulse-beats was not measured by means of a watch until after the publication, in 1707, of Sir John Floyer's book, "The Physician's Pulse-watch, or an Essay to explain the old art of feeling the Pulse." In the time of Harvey and long afterwards physicians contented themselves with estimating the character of the pulse, rather than its precise rate.

[12] Dr. Norman Moore suggests that this young nobleman was possibly Philip Herbert (_d._ 1669), son of Philip Herbert, the second son of Henry, Earl of Pembroke (_d._ 1648), created Earl of Montgomery 1605-1606, and Lord Chamberlain.

Transcriber's Notes:

Words surrounded by _ are italicized.

Words surrounded by = are bold.

In this e-text, [~o] represents diacritical mark tilde (~) above the letter o whereas [-e] represents a straight horizontal line (-) above the letter e.

Obvious printer's errors have been repaired, other inconsistent spellings have been kept, including inconsistent use of hyphen (e.g. "blood-vessels" and "blood vessels"), proper names (e.g. "Micklethwayte" and "Micklethwaite") and accent (e.g. "Tabulæ" and "tabulae").