Chapter 27

As the _Titanic_ was leaving her pier at Southampton there came a sound like the booming of artillery. The passengers thronging to the rail saw the steamship _New York_ slowly drawing near. The movement of the _Titanic's_ gigantic body had sucked the water away from the quay so violently that the seven stout hawsers mooring the _New York_ to her pier snapped like rotten twine, and she bore down on the giant ship stern first and helpless. The _Titanic_ reversed her engines, and tugs plucked the _New York_ away barely in time to avoid a bad smash. If any old sailors regarded this accident as an evil omen, there is little reason to think the thing affected the spirits of the passengers on the great floating hotel. As the ship passed the time of day by wireless with her distant neighbors out of sight beyond the horizon of the ocean lanes, she reported good weather, machinery working smoothly, all going well.

For some reason the great fleet of icebergs which drifts south of Cape Race every summer moved down unusually early this year. The _Carmania_, three days in advance of the _Titanic_, ran into the ice-field on Thursday. The ship at reduced speed dodged about, avoiding enormous bergs along her course, while far away on every hand glinted the shining high white sides of many more of the menacing ice mountains. Passengers photographed the brilliant monsters. The steamship _Niagara_, many leagues astern, reported a slight collision, with no great harm done. That was enough. Captain Dow retraced his course to the northeast and, after an hour's steaming, laid a new course for Fire Island buoy. The presence of the great bergs and accompanying masses of field-ice so very early in the season was most unusual.

Into this desolate waste of sea came the _Titanic_ on Sunday evening. She encountered fog, for the region is almost continuously swathed in the mists raised by the contact of the Arctic current with the warm waters of the Gulf Stream. Scattered far and wide in every direction were many icebergs, shrouded in gray, invisible to the eyes of the sharpest lookouts, lying in wait for their prey.

Not only were the bergs invisible to the keenest eyes, but the sudden drop in the temperature of the ocean which ordinarily is the warning of the nearness of a berg was now of no avail; for there were so many of the bergs and so widely scattered that the temperature of the sea was uniformly cold. Moreover, the submarine bell, which gives warning to navigators of the neighborhood of shoal water, does not signify the approach of icebergs. The newest ocean giant was in deadly peril, though probably few of her passengers guessed it, so reassuring are the huge bulk, the skilful construction, the watertight compartments, the able captain and crew, to the mind of the landsman. Dinner was long past, and many of the passengers doubtless turned to thoughts of supper after hours of talk or music or cards; for there were not many promenading the cold, foggy decks of the onrushing steamship.

The _Titanic_ was about eight hundred miles to the southeastward of Halifax, three hundred and fifty miles southeast of treacherous Cape Race, when her great body dashed, glancing, against an enormous berg. The discipline and good order for which British captains and British sailors have long been noted prevailed in this crisis; for it is proven by the fact that the rescued were nearly all women and children.

From that rich, rushing, gay, floating world, with its saloons and baths and music-rooms and elevators, now suddenly shattered into darkness, only one utterance came. Phillips, the wireless operator, seized his key and telegraphed in every direction the call "S O S!" Gossiping among telegraphers hundreds of miles apart, messages of business import, all the scores of things that fill the ocean air with tremulous whisperings of etheric waves, began to give over their chattering. Again and again Phillips repeated the letters which spell disaster until the air for a thousand miles around was electrically silent. Then he sent his message:

"Have struck an iceberg; badly damaged; rush aid; steamship _Titanic_; 41.46 N., 50.14 W."

There was no other ship in sight. Far as the eye could reach no spot of light broke the gray darkness; yet other ships could hear and read the cry for help, and, wheeling in their courses, they drove full speed ahead for the wreck. The _Baltic_, two hundred miles to the eastward, bound for Europe, turned back to the rescue; the _Olympic_, still farther away, hastened to the aid of her sister ship; the _Cincinnati, Prince Adelbert, Amerika,_ the _Prinz Friederich Wilhelm_, and many others, abandoned all else to fly to help those in danger. Nearest of all was the _Carpathia_, bound from New York for Mediterranean ports, only sixty miles away. And as they all, with forced draft and every possible device for adding to speed, dashed through the misty night on their errand of mercy, Phillips, of the _Titanic_, kept wafting from his key the story of disaster. The thing he repeated oftenest was: "Badly damaged. Rush aid." Now and then he gave the ship's position in latitude and longitude as nearly as it could be estimated by her officers as she was carried southward by the current that runs swiftly in this northern sea, so that the rescuers could keep their prows accurately pointed toward the wreck. Soon he began to announce, "We are down by the head and sinking rapidly." About one o'clock in the morning the last words from Phillips rippled through the heavy air, "We are almost gone."

The crew were summoned to their stations; the lifeboats and liferafts were swiftly provisioned and furnished with water as well as could be done. Yet this provision could hardly have been very extensive, since it has long been an accepted axiom of the sea that the modern giant ships are indestructible, or at least unsinkable.

"Women and children first," the order long enforced among all decent men who use the sea, was the word passed from man to man as the boats were filled, the boatfalls rattled, and the frail little cockleshells were lowered into the calm sea. What farewells there were on those dark and reeking decks between husbands and wives and all other men and women of the same family one can hardly dare think about. Steadily the work of filling the boats and lowering away went on until the last frail craft had been dropped upon the ocean from the sides of the liner and the whole little fleet rose and fell on the sea beside the great black hulk. And when the last crowded boat had come down and there was no possibility of removing one more human being from the wreck, there were still more than fifteen hundred men on her decks. So far had belief in the invulnerability of the modern ship curtailed sane and proper provision for taking care of her people in time of calamity.

One can imagine with what frantic but impotent hope, as the sinking decks and menacing plash of waters within told of the imminent last plunge, those thousands of eyes strained at the misty wall of grayish black that enclosed them on every hand. Not one gleam of light in any quarter. The last horrible gurglings within the waterlogged shell of steel that a little while before had been the proudest ship of all the seas told unmistakably that the end was at hand. Down by the head went the giant _Titanic_ at twenty minutes past two o'clock on Monday morning, April 15th. And she took fifteen hundred people with her.

Four hours passed before the shivering people in the small boats heard the siren whistle that announced the approach of a steamship from the south. There was a heavy fog and they could not see one hundred fathoms off over the clashing and grinding ice that floated in fields on every side. Soon after seven o'clock in the morning the ship came in sight and presently hove to among the fleet of boats and liferafts--the steamship _Carpathia_, out of New York on April 11th for Mediterranean ports. She began at once to take aboard the survivors, and in a few hours had every boat hoisted aboard. The _Olympic_ and _Baltic_, learning by wireless that the rescues had all been effected, proceeded on their way.

The _Virginian_ and the _Parisian_, which arrived at the scene of the disaster a few hours later, could find no sign of any living person afloat, though they cruised for a long time among the wreckage before standing away on their courses. The _Carpathia_ at first was headed for Halifax, but upon learning by wireless that that harbor was ice-bound, Mr. J. Bruce Ismay, chairman of the Board of Directors of the White Star Line, suggested that the ship head for New York. This was done. The _Carpathia_, with nine hundred passengers of her own and the seven hundred survivors, reached New York in safety.

The sad international tragedy of the sinking of the _Titanic_ touched men's souls more deeply than any other disaster in many years. To English-speaking races in particular the horror of the occasion pressed close home; for here was the best of British ships bearing many of the most prominent of America's people. To these seasoned voyagers, crossing the Atlantic had become a mere pleasant trifle, seeming no more dangerous than an afternoon's shopping in town. Then suddenly there was thrust upon all of them that ancient, awful knowledge that "in the midst of life we are in death."

Both American passengers and English crew lived up to the best traditions of their race. There was no panic, no fighting for places in the boats on the doomed ship. On the contrary, people refused to believe in the imminence of danger. The idea that the ship was unsinkable had been so borne in on them that even when summoned upon deck and ordered to put on life-belts, many of them refused. In the first boats gotten away from the ship, there were not many people. Some refused to climb down through the deep blackness into the tiny craft. They thought the tumult all an empty scare that would soon pass.

When the steady, ominous settling of the huge ship's bulk broke through this shallow confidence, there was a solemn change. Grand and tender scenes there were on those sinking decks; of husbands and wives parting with the utterance of a hope, turned suddenly to terror, that they would soon meet again; of other wives who refused to leave their husbands and deliberately stayed to share their fate. Few of the more noted passengers were among those saved. Bruce Ismay, director of the steamship line, was one. The captain went down with his ship, as did most of his officers, though some of the latter saved themselves by clinging to the wreckage which rose after the vessel's plunge. While she was sinking her band still played "Nearer, my God, to thee," and other earnest hymns. Death did not find the old Saxon stock cringing from him with hysteria and frenzy. Sudden as was his coming, wholly unexpected as was his hideous visage, he was met with the calm courage which is the best tradition of the race.

And what have been the consequences of this overwhelming tragedy? An investigation was immediately begun in America by the United States Government. Another, slower, dignified and ponderous, was afterward undertaken by the British Government. Both of them in the end attributed the disaster to practically the same cause, the speed mania which has overtaken the nations, the heedlessness of man's over-confidence which takes risks so many times successfully that it grows to forget that risks exist.

The _Titanic's_ captain wanted to make a record on her maiden voyage. His directors wanted him to make a record. That would mean increased advertisement and increased traffic for their line. So in the face of danger, knowing there were icebergs all around him, the captain rushed his ship blindly ahead. The chance of his actually hitting an iceberg was scarce one in a hundred. So he took the chance. The probability that if he did strike an iceberg it could do irreparable damage to his stout ship, was scarce one in a hundred. So he took that chance also. He gambled with Death, as a thousand speed-driven captains had gambled before. This time it was Death's turn to win.

A gamble even more reprehensible was that of the steamship companies, who had grown so sure their ships would not sink that they no longer provided sufficient means of escape from them. Why load a vessel down with useless life-boats, which only hung the year in and year out, blocking up space? Every foot of that space was valuable. It might make room for an extra passenger, or provide an extra amusement to draw traffic. What voyager ever counted life-boats, or worked out the awful calculation, so obvious now, that there was only rescue space provided for one-third of the number of souls aboard? Was not the ship "unsinkable" after all?

The _Titanic_ is gone. Our sorrow for her is becoming but a memory. Our ships carry lifeboats sufficient now; they are compelled to by law. And our sea captains run on safer lines; that, too, the law has made compulsory. But it will be long before man's overweening self-confidence rises from the shock which has been given to his belief in his mechanical ability. Nature is not conquered yet. Ocean has still a strength beyond ours. Ships are not unsinkable; and Death will still take his toll of bold men's lives in the future as he has done in the past. We know that cowardice costs more than courage, but it is not so tragically costly as blind foolhardiness.

OUR PROGRESSING KNOWLEDGE OF LIFE SURGERY PERPETUATES THE BODY'S ORGANS

A.D. 1912

GENEVIEVE GRANDCOURT Prof. R. LEGENDRE

Several years ago a wealthy Swedish manufacturer of dynamite left, by his will, a fund for the providing of a large prize to be conferred each year upon the person who has accomplished most for the peaceful progress of mankind. This annual sum of forty thousand dollars, which is called from its donor the "Nobel prize," was, in October, 1912, conferred upon a surgeon, Dr. Alexis Carrel, for his remarkable work in the study of the life of the tissues and organs which exist in the human body.

Even before this public recognition of his work, Dr. Carrel had in the summer of 1912 created a furor among the savants of Paris by the announcement of what he had accomplished. Carrel, though a native-born Frenchman, is an American by education and citizenship, and the French were at first inclined to challenge the value of his work. We therefore present here a "popular" scientific account of what he had achieved, reprinted by permission from the _Scientific American_. Then comes the grudging approval of Professor Legendre, the noted "Preparator of Zoology," head of that section in the National Museum of Paris.

Briefly stated, the impressive step which science has here taken, is the preservation of life in the heart and other organs so that these may be taken out of the body and yet kept alive for months. With smaller animals Carrel has even accomplished the actual transferrence of organs from one individual to another. As for the simpler bodily tissues, it now seems possible to preserve these indefinitely outside the body, not only alive but in excellent health and ready to reassume their functions in another body.

GENEVIEVE GRANDCOURT

THE "IMMORTALITY" OF TISSUES

A very evident disadvantage under which medical science has labored has been the impossibility of watching the chemical process set in motion by substances introduced into the body. For this reason various experimenters, from time to time, have attempted to "grow tissues" artificially, in such manner that their development, functions, and decay--under both healthy and diseased conditions--might be studied under the microscope. The only way in which this could be done would be to take a piece of living tissue from the body, and cause its cells to multiply; tissue being made up of an aggregation of cells.

Science has failed to produce a single living cell, that is, a cell which will undergo the process of nuclear division (growth) which is the prime condition of its being; and it seemed equally impossible to cause a cell already living to undergo the same process if deprived of the circulation of the blood. Therefore, when in 1910 it was announced that Dr. Alexis Carrel with his assistant, Dr. M. T. Burrows, had succeeded, scientific credulity was taxed. A well-known French savant expressed the opinion before the Society of Biology in Paris, that as others experimenting along these lines, had witnessed only degeneration and survival of cells, this phenomenon was all Carrel's discovery amounted to. In view of past experience, indeed, the chances were in favor of a mistake. In 1897, Leo Loeb said that he had produced this artificial growth both within and without the body. Obviously, such development within the organism where the process of utilizing the body-fluids, etc., follows the same course as in nature, takes on the character of grafting rather than of cultivating in a culture medium. As to causing the external growth, it was ten years later before it seems first to have succeeded. In 1907 Harrison, from Johns Hopkins University, furnished details of his research in such form as to be convincing. But his work had reference to the growth of tissues only of coldblooded animals, he having cultivated artificially, nerve fibers from the central nervous system of the frog.

Carrel's work consisted in extending Harrison's method to apply to warm-blooded animals, including, of course, mammals; he having primarily in view at this time a more precise knowledge of the laws governing the restoration of tissues, for example, after serious surgical wounds. He and his assistant worked steadily to this end, and succeeded. The tissues of the higher animals, including man, can now be developed in a culture, and such development can be made to correspond to a rigidly precise technique. The feat is accomplished by putting minute pieces of living tissue into a plasmatic (blood) medium which will coagulate. So complicated is this apparently simple matter in its application that only the most exquisite surgical skill is proof against incalculable modifications in results.

Having obtained evidence that tissue can be cultivated in accordance with a formula that may be relied upon to give definite results, the effort was made to grow artificially the various malignant (cancerous) tissues, in turn, of chicken, rat, dog, and human being. Cancerous tissue invariably developed cancer, and so rapidly and extensively that the growth could be observed with the naked eye.

It now became evident that, under the right circumstances, the artificial growth of tissues could be utilized in the study of many problems; such as malignant growth of tissue; certain problems in immunity, as, for example, the production of antitoxins of certain organisms; the regulation of the growth of the organism, or of different parts of the organism; rejuvenation and senility; and the character of the internal secretions of the glands, such as the thyroid which plays a role most important in physical and mental development. The difficulty lay in the fact that the artificial growth was so very short-lived. It was found that by passing the growth into a new medium, and repeating the process, the tissues would begin to grow again; but their life even under these circumstances was limited at the most to twenty days. This was manifestly too short a time in which to study the fundamental questions to which the researchers had addressed themselves. Thereupon, study was taken up to determine the question as to _what made these tissues die_. It was found that, apparently as incidental to growth, there was the process of decay, due to an _inability of the tissues to eliminate waste products._

On January 17, 1912, experiments were commenced to determine whether these effects could be overcome. The observations were on the heart and blood-vessels, artificially grown, of the chicken fetus. These growths were put into a salt solution for a few minutes at different periods of their growth, and then placed in a new plasmatic medium. It was found that by following this method, the tissues could be made to live indefinitely. When an animal is in the early stages of its development, the growth of its tissues is necessarily greater as it matures, there being steady diminution after a certain age until the growth altogether ceases, and the size of the animal is determined. But it was found by subjecting these artificial growths to washings in salt solution that the mass was _fifteen times greater at the end of than at the commencement of the third month, showing that they do not grow old at all!_ In the artificial growth the problem of senility and death is solved.

It was the announcement of this "permanent life of tissues" that caused such a furor in Paris last summer, and several eminent scientists to demand ocular demonstration, because "the discovery, if true, constituted the greatest scientific advance of a generation."

The following summary of this interesting and vitally important and epoch-making work of Carrel is translated from an article published in Paris recently by Professor Pozzi, who witnessed the experiments:

"Carrel found that the pulsations of a fragment of heart, which had diminished in number and intensity _or ceased_, could be revived to the normal state by a washing and a passage. In a secondary culture, two fragments of heart, separated by a free space, beat as strongly and regularly. The larger fragment contracted 92 times a minute and the smaller 120 times. For three days, the number and intensity of the pulsations varied slightly. On the fourth day, the pulsations diminished considerably in intensity. The large fragment beat 40 times a minute and the little fragment 90 times. The culture was washed and placed in a new medium. An hour and a half after, the pulsations had become very strong. The large fragment contracted 120 times a minute and the small fragment 160 times. At the same time the fragments grew rapidly. At the end of eight hours they were united and formed a mass of which all the parts beat synchronically."

Experiments to date seem to establish that the connective tissue, at any rate, is "immortal."

From this research, it is possible to arrive at certain logical conclusions, which, however, it remains for the future to confirm. One, and the most important, is that the normal circulation of the blood does not succeed in freeing all the waste products of the tissues, and that this is the cause of senility and death. Were science to find some way to wash the tissues in the living organism as they have been washed in these cultures, man's life might be indefinitely prolonged.

R. LEGENDRE

The Nobel prize in medicine for 1912 has just been awarded to Dr. Alexis Carrel, a Frenchman, of Lyon, now employed at the Rockefeller Institute of New York, for his entire work relating to the suture of vessels and the transplantation of organs.

The remarkable results obtained in these fields by various experimenters, of whom Carrel is most widely known, and also the wonderful applications made of them by certain surgeons have already been widely published.

The journals have frequently spoken lately of "cultures" of tissues detached from the organism to which they belonged; and some of them, exaggerating the results already obtained, have stated that it is now possible to make living tissues grow and increase when so detached.