Part 22

Vesicatories depend upon the same principle. Their first effect is to fill with blood the cutaneous capillary system, where they are applied, to produce in it a sudden erysipelas, and then to occasion a copious serous exhalation under the raised epidermis. They effect in a few hours what most cases of erysipelas do in many days; for we know that most of them terminate by vesicles which are raised above the skin. In burning, carried sufficiently far to be more than a rubefacient, and yet not so as to produce the horny hardening, there is also a sudden increase of exhalation under the raised epidermis. In general the production of every cutaneous bladder is always preceded by an inflammation of the external surface of the skin. This phenomenon is not exclusively confined to this system. We have seen the serous, as soon as it is laid bare and irritated considerably, redden in a short time by the passage of the blood into its exhalants; which constitutes an inflammation to which often succeeds a copious exhalation of milky or other kind of serum. This exhalation does not remain upon the surface, and does not form vesicles there, because it has no epidermis; this is the only difference between these phenomena, which at first view do not appear to be the same in the serous and cutaneous systems.

It is not only the irritation of the cutaneous organ which makes the blood pass into the external capillary system. Whenever the heart is powerfully excited and it accelerates the course of this fluid, it always tends to go into it; this is what is evidently seen, 1st, after violent running; 2d, in the hot period of a paroxysm of fever.

Upon this subject I will make a remark which appears to me to be very important; it is that the capillary system of the face is, more than that of all the other parts of the skin, exposed to be thus penetrated with blood. 1st. This is evident in the two cases of which I have just spoken, and in which the action of the heart is increased. 2d. In the passions, the skin remains the same in the other parts, whilst that of the face suddenly becomes pale or red. 3d. We know that physicians frequently examine the state of the facial capillary system, which is almost always affected by the state of the internal viscera, and is full of blood or empty, according as it is sympathetically influenced. 4th. In various kinds of asphyxia, in those especially produced by submersion, by the vapour of charcoal, by strangulation, &c. the face is uniformly of a violet colour from the passage of the black blood into its external capillary system, into which it is brought by the arteries. Oftentimes the neck and the upper part of the chest are also livid; but there is never a discoloration of the inferior parts. 5th. In many diseases, in which death takes place by a kind of asphyxia, because the lungs are the first interrupted, the dead bodies have a violet-coloured and swollen face; this may be easily observed by all who frequent dissecting rooms. There are a hundred subjects in which the head has this lividity, to one in which it is observed in the inferior parts. 6th. Most cases of apoplexy produce the same lividity of the face.

To what is this extreme susceptibility of the facial capillary system to admit the blood owing? Three things, I think, principally contribute to it. 1st. The course is already opened to this fluid, since the redness of the cheeks necessarily supposes its presence in them, it only increases in quantity; whereas when another part of the dermoid surface becomes red, all the blood which enters it is almost accidental. 2d. The anatomical arrangement of the capillary system is more favourable to this passage there than elsewhere; for it appears that the communications of this system with the arteries of the chorion are more free. What proves this is, that in injections the face is coloured with great ease. There is undoubtedly no anatomist who has not been struck with this phenomenon, especially in children, in whom if the coarse injections of our dissecting rooms succeed at all, the face becomes wholly black, whilst the fluid penetrates but very little into the other parts of the cutaneous system. 3d. It appears that there is a greater sensibility in the face; in fact the same irritant brings blood there, which does not make it flow to any other place. For example, a blow equal to a box on the ear does not redden the skin of the arm, whilst it suddenly inflames the cheeks.

The blood disappears from the facial capillary system as it enters it; in an instant the passions will successively produce there the bright red of a paroxysm of fever, the whiteness of syncope and all the intermediate shades. It is even the extreme ease with which this fluid penetrates this system, that renders the face well adapted to serve as a kind of picture, which the passions paint by turns with a thousand shades, that are effaced, altered, modified and return again according to the state of the mind.

I would observe upon this subject that the passions have in the face three means of expression; 1st, the capillary system, a means wholly involuntary, and which often betrays what we wish to conceal; 2d, the muscular motion, which, by contracting or expanding the features, expresses the melancholy or gay emotions, and to which belongs as effects, the various wrinkles of which we have spoken; 3d, the state of the eye, an organ, which, as Buffon has remarked, not only receives the sensations, but also expresses the passions. The two last means are to a certain extent voluntary; we can at least disguise them; whereas we cannot deceive by the first. The actor imitates anger, joy, &c. because we can give these passions by contracting the eye-brows, by dilating the face in laughing, &c. But it is the rouge of the actress that imitates modest chastity; it is by removing this rouge that she imitates the paleness of fear, horror, &c.

I will add another essential observation in respect to the facial capillary system; it is that it appears that its tendency to receive blood, disposes it to become the more frequent seat of many affections. We know, 1st, that erysipelas is much more frequent in this than in other parts; 2d, that the variolous pustules are remarkably conspicuous here; 3d, that many eruptions are more abundant here than elsewhere.

From all that we have just said, it is evident that it is necessary to distinguish two portions in the capillary system exterior to the chorion. 1st. One is constantly filled with the colouring substance of the skin, a substance which appears to be stagnant like that of the hair of the head, and that of the hair of the body, which is subjected only to the slow and insensible motion of composition and decomposition and which never exhibits that sudden increase or diminution of which we have just spoken. 2d. The second is constantly pervaded by many fluids which continually succeed each other there, and which constantly escape by transpiration, and which are replaced by the blood, that insinuates itself into this portion of the capillary system. These two portions are entirely independent, and have probably no kind of communication.

It appears that at the instant of death there remains a certain quantity of the white fluids in the second portion of the exterior capillary system; the following experiment, which I have frequently made, proves it; by plunging a portion of skin into boiling water, and leaving it there an instant, the epidermis is raised up, not as a whole as in a blister, but in an infinite number of small vesicles which are formed suddenly on its surface, and which contain a serous fluid, that escapes as soon as we open these vesicles.

_Papillæ._

We call by this name those small eminences that arise from the external surface of the chorion, and which, piercing the capillary net-work of which we have just spoken, become by their extremities contiguous to the epidermis. These eminences are very evident in the palm of the hand and the sole of the foot, where they are regularly arranged, in the form of small curved striæ in different directions. We see them through the epidermis, notwithstanding its thickness in these places. But they are seen especially when this has been in any way removed, as by maceration, ebullition, &c. If we cut longitudinally a portion of the chorion of the foot, with its epidermis adhering to it, we see between them along the divided edge, a line in the form of a curved thread, which arises from these small eminences placed at the side of each other.

In some other parts of the skin, we distinguish the papillæ in a very evident manner; but in a great number, the epidermis being removed, we see only a surface, slightly uneven from some small eminences, especially towards the orifices through which the hairs and the vessels pass, but we do not discover those regularly arranged eminences, the papillæ properly so called.

We must not mistake for them the numerous and very evident prominences, which render the skin of some subjects extremely rough. These prominences are formed by small cellular, vascular or nervous bunches, by sebaceous glands, &c. which are found near the small openings by which the chorion opens under the epidermis, and usually transmits the hairs. These bunches, lodged in the small oblique canals which are terminated by these openings, raise the external side of them and thus form this prominence. The following very curious experiment proves this arrangement; when the skin is macerated for two or three months, or even less, on the one hand these little bunches in which there is almost always a little fat, are changed into that white, thick, unctuous matter, analogous to spermaceti, into which fat kept a long time in water is always converted; and on the other, the foramina enlarging, as we have seen, and the skin changing into a kind of pulp, we can easily remove it all around these little prominences, and see that they are continued with the fat which fills the meshes of the subjacent chorion, and which is also changed into a hard matter.

Injections have evidently proved to me that there were vessels in these cellular bunches, and I have been convinced of it for some time past by the dissection of some subjects that died of scurvy, in whom the spots commenced by very small ecchymoses, similar as it were to flea-bites, and which occupied these little eminences. The petechiæ of adynamic fevers have a different appearance; but they belong also to an extravasation of blood in the cellular texture, occupying the small pores which open on the exterior of the chorion to transmit the vessels, the hairs, &c. The more prominent these eminences are, of which we have spoken, the more uneven is the skin. In general they are more frequent on the extremities and on the back, than on the anterior part of the trunk. In the extremities there are more of them in the direction of extension, than in that of flexion.

We attach the idea of a beautiful skin, to that in which these small tubercles are not found, and in which the chorion is united at its external surface. Women have commonly this last arrangement more evident than men. The epidermis which covers these eminences very often scales off at that place, especially from strong friction, which contributes still more to render the skin uneven, rough and harsh to the touch where they exist, which might induce a belief that they are formed by it, though it is always only accessory to them. Where it is very thick, as in the palm of the hand and the sole of the foot, it cannot be raised, and these small cutaneous tubercles are never seen. In the face where many vessels pass from within outwards, by the little pores of which we have spoken, we meet with hardly any more of them. The papillæ scattered among these eminences, are in general very slightly apparent in the places where they exist.

All anatomists attribute to these last a nervous structure; they regard them as the termination of all the nerves that go to the skin, and which, according to them, are expanded to form these, after having first left their external covering. Some even say that they have traced filaments even into the papillæ; I confess that I have never been able to do it. In the ordinary state, the density of the chorion and the extreme delicacy of the filaments, are evidently an obstacle to it. In the state of long continued maceration, in which the chorion becomes pulpy and in which we might consequently trace these filaments, were it ever possible, it cannot be done. I do not however deny the texture attributed to the papillæ. The acute sensibility of the skin seems even to suppose it; but it is only analogy and not demonstration, which establishes this anatomical fact; indeed all the other senses, whose organs are so sensible, have the portion of them which receives the impression of bodies continuous with a nerve.

_Action of different bodies upon the Dermoid Texture._

In most of the other textures, we have only considered this action in the dead body, because during life, these textures always removed from external bodies, cannot be influenced by them. Here we can regard it in a double relation, since the skin is incessantly in contact with almost all the bodies of nature.

_Action of Light._

Light evidently acts upon the dermis. Removed from its influence, men are blanched, if we may so say, like plants. Compare the inhabitant of a city, who is never exposed to the influence of the sun, with the peasant who constantly is, and you will see the difference. It appears that it is the light and not the heat which produces the effect of which I have already spoken; for individuals who live in a warm temperature, but removed from the solar light, become white like those of cold countries. Thus we know that some men who keep their chambers always very hot, are whiter than others who, living in a less hot atmosphere, are constantly exposed to the sun. We might remain forever in a bath of a temperature equal to the warmest seasons, and the skin would not blacken. Apartments for study which are warmed with stoves, and in which men remain as long as the labourer at his plough, are as warm as the atmosphere of summer, and yet the skin of those who occupy them never becomes darker. Besides an irresistible proof is that the clothing which does not prevent the action of caloric upon the skin, and which offers a barrier to the rays of light only, prevents the cutaneous colouring that takes place upon the parts which the light immediately strikes, as upon the hands, the face, &c.

I do not speak of the solar influence upon the vital forces of the skin, as in cases in which sun-strokes produce erysipelas, or as when light is employed medicinally to recall the life of a part; but it is only in relation to the dermoid texture that I consider its action.

_Action of Caloric._

The action of caloric upon the skin exhibits very different phenomena, according to the degree of it that it is applied.

1st. A warm atmosphere expands the dermoid texture, increases its action, and makes most of the fluids which form the residue of nutrition and digestion, pass off by the exhalants.

2d. When contracted by cold, this texture refuses to admit those fluids, which then go off principally by the urine.

3d. The insensible change from one to the other of these two states, does not disturb the functions. When this change is sudden, there are almost always alterations in different organs, because the fluids destined to pass out, cannot vary their direction as rapidly towards this or that organ, as the cutaneous excitement produced by the sudden changes from heat to cold.

4th. The skin resists a temperature much greater than that of the body; it opposes an insurmountable barrier to the external caloric, which tends to an equilibrium in animate as well as inanimate bodies. Thus whilst these last are penetrated with this fluid in a medium warmer than themselves, and soon acquire the temperature of this medium, living bodies remain at the same degree, how much greater soever the surrounding heat may be to their own. The curious experiments of the English physicians have placed this truth, as it respects man, beyond a doubt. It is unnecessary to give the detail of these well known experiments, in which the mercury was seen to descend in the thermometer, when the bulb was placed in the mouth and in which the skin became covered, in a heated room, with the aqueous vapours of the air, which the greater cold of the body condensed upon its surface. A slight attention to animals with cold blood, living in warm climates, proves the same thing. I will make one remarkable observation upon this point, it is, that most reptiles, whose temperature is much less than that of the mammalia and of birds, and who consequently are brought much nearer than them to the temperature of winter, cannot however support it. They become torpid and sleep in subterraneous places, the heat of which remains nearly uniform like that of cellars, and do not awake till the milder temperature of spring stimulates them.

5th. The skin, in very cold climates, seems to be on the other hand an obstacle which prevents the internal caloric from suddenly escaping and thus placing the body in equilibrium with the surrounding medium. This is evident in countries near the pole. Upon this subject an observation the reverse of the preceding can be made; it is that the cetaceous animals inhabit seas the temperature of which is most unlike their own. Whales are sought for especially in the latitudes of Greenland, Spitzbergen, &c. Why do fishes with warm blood delight in the frozen seas, whilst the amphibious animals with cold blood prefer the burning heat of the sun? I know not.

Let us observe that most of the internal organs when exposed in solutions of continuity, have not the faculty of preserving as well as the skin, a degree of independent temperature. They become cold or hot sooner than it as long as they remain healthy. The intestine brought out of the abdomen in the operation for hernia, a muscle laid bare, &c. &c. exhibit this phenomenon; thus in order to give them this faculty of having an independent temperature, nature inflames them, and they thus constantly preserve their heat, whatever may be that of the surrounding medium. The mucous surfaces next to the skin resist the surrounding temperature the most, as is seen in prolapsus of the rectum, in inversion of the anus, &c. This difference among the different systems is probably owing to that of their structure.

6th. When the action of caloric is carried to a very considerable extent, it begins to act upon the skin, and its effects are the more evident in proportion as it is the more intense. 1st. The slightest of these effects is to produce an evident redness, a kind of erysipelas; the caloric then acts like a simple rubefacient. 2d. The second is to redden the skin and then to produce vesicles on it. 3d. In the third there is a real horny hardening, a crisping of the fibres of the chorion which contract, like those of all the animal textures exposed to too strong a degree of heat. 4th. In the fourth and last effect, the dermoid texture is burnt, blackened and reduced to mere carbon. These different degrees of burning arise only from different degrees of caloric. I would observe that in the two first effects, this fluid acts upon the vital forces, and that these two effects cannot consequently take place except during life. The two last are exerted only upon the texture of the organ; thus they take place after death precisely as before. Cooks often employ the horny hardness, to give to the skin a hardness and brittleness necessary in some kinds of cooking.