Part 6

=CATAPLASMATA, POULTICES.=--Poultices are soft solid preparations used for the purpose of applying heat and moisture to localized areas of the body. Poultices may also be made the means of applying counterirritant drugs.

=Cataria (Catar.), Catnep, N.F.= (Catmint).--Leaves and flowering tops.

ACTION AND USES: Aromatic carminative, without advantage over peppermint.

DOSAGE: 4 Gm. or 1 drachm (N.F.).

_Fluidextractum Catariae (Fldext. Catar.), Fluidextract of Catnep, N.F._--Catnep (100%). Absolute alcohol content about 35 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=Caulophyllum (Caulophyl.), Caulophyllum, N.F.= (Blue Cohosh, Papoose Root, Squaw Root).--Rhizome and roots.

ACTION AND USES: Said to be diuretic and emmenagogue; has not been adequately studied.

DOSAGE: 0.5 Gm. or 8 grains (N.F.).

_Fluidextractum Caulophylli (Fldext. Caulophyl.), Fluidextract of Caulophyllum, N.F._--Caulophyllum (100%). Absolute alcohol content about 60 per cent.

DOSAGE: 0.5 Cc. or 8 minims (N.F.).

=Centaurium (Centaur.), Centaury, N.F.=--Flowering plant.

ACTION AND USES: Bitter stomachic; without advantage over gentian. Also used in "female remedies," but probably useless.

DOSAGE: 2 Gm. or 30 grains (N.F.).

=*Cera Alba (Cer. Alb.), White Wax, U.S.P.=--Yellow wax bleached.

ACTION AND USES: Used in the preparation of emollient ointments, and to raise the melting point of mixtures of oils and fats.

_Ceratum (Cerat.), Cerate, U.S.P._ (Simple Cerate).--White wax (30%) and benzoinated lard.

=*Cera Flava (Cer. Flav.), Yellow Wax, U.S.P.= (Beeswax).

ACTION AND USES: Used in the making of plasters and of ointments in which the color is not objectionable.

=CERATAE, CERATES.=--Cerates are solid ointment-like preparations containing wax to prevent them from becoming soft at ordinary room temperature.

=Cerevisiae Fermentum Compressum (Cerev. Ferm. Compr.), Compressed Yeast, N.F.=--The commercial compressed yeast.

ACTION AND USES: For use in making fermented milk (Lac Fermentatum), which see under =Lac Vaccinum=.

=Cerii Oxalas (Cerii Oxal.), Cerium Oxalate, U.S.P.=--A mixture of the oxalates of cerium, didymium, lanthanum, and other associated elements.

White or pinkish, odorless, tasteless powder. Insoluble in water, alcohol and ether.

ACTION AND USES: Formerly used for the treatment of chronic vomiting but probably without value.

DOSAGE: 0.2 Gm. or 3 grains (U.S.P.), in powders, cachets or capsules.

=Cetaceum (Cetac.), Spermaceti, U.S.P.=--A solid fat from the sperm whale.

White, nearly odorless, unctuous masses, with a bland, mild taste. Insoluble in water and nearly insoluble in cold alcohol.

ACTION AND USES: Used as a component of cerates and cold creams.

=CHARTAE, PAPERS.=--Papers are pieces of unsized paper saturated with or pieces of hard-surfaced papers coated with a medicinal substance.

=Chimaphila (Chimaph.), Chimaphila, N.F.= (Pipsissewa).--Leaves.

ACTION AND USES: Obsolete; no definite indications for its use. Has been described as "tonic, astringent, diuretic."

DOSAGE: 2 Gm. or 30 grains (N.F.).

_Fluidextractum Chimaphilae (Fldext. Chimaphil.), Fluidextract of Chimaphila, N.F._--Chimaphila (100%). Absolute alcohol content about 40 per cent.

DOSAGE: 2 Cc. or 30 minims (N.F.).

=Chionanthus (Chionanth.), Chionanthus, N.F.= (Fringe Tree Bark).--Bark of the root.

ACTION AND USES: Obsolete; no definite indications for its use. Formerly used by eclectics and homeopaths in hepatic disorders and syphilis.

DOSAGE: 2 Gm. or 30 grains (N.F.).

_Fluidextractum Chionanthi (Fldext. Chionanth.), Fluidextract of Chionanthus, N.F._--Chionanthus (100%). Absolute alcohol content about 60 per cent.

DOSAGE: 2 Cc. or 30 minims (N.F.)

=Chirata (Chirat.), Chirata, N.F.= (Chiretta).--Plant.

ACTION AND USES: Bitter stomachic, similar to and without advantage over gentian.

DOSAGE: 1 Gm. or 15 grains (N.F.).

_Fluidextractum Chiratae (Fldext. Chirat.), Fluidextract of Chirata, N.F._--Chirata (100%). Absolute alcohol content about 40 per cent.

DOSAGE: 1 Cc. or 15 minims (N.F.).

=Chloral Camphoratum (Chloral Camph.), Camphorated Chloral, N.F.=--Equal parts of hydrated chloral and camphor.

An oily liquid with a camphoraceous odor.

ACTION AND USES: Local rubefacient and analgesic

=*Chloralum Hydratum (Chloral. Hydrat.), Hydrated Chloral, U.S.P.= ("Chloral," Chloral Hydrate).--CCl{3}.CHO + H{2}O.

Colorless, transparent crystals, with an aromatic, penetrating odor and a bitterish, caustic taste. Very soluble in water (1:0.25) and in alcohol (1:1.3).

ACTION AND USES: A reliable hypnotic in moderate doses, inducing a condition closely resembling that of normal sleep. Used for the relief of insomnia and nervousness, and for the control of convulsions and spasms. Should be used with special caution in cases of weakened heart or blood vessels. Continued use is likely to produce a habit.

DOSAGE: 0.5 Gm. or 8 grains (U.S.P.), in solution. Decomposed by alkalies; should not be dispensed in liquids containing both bromides and alcohol.

_Mistura Chloralis et Potassii Bromidi Composita (Mist. Chloral. et Pot. Brom. Co.), Compound Mixture of Chloral and Potassium Bromide, N.F._ (Chloral and Bromide Compound).--Hydrated chloral (20%), potassium bromide (20%), extract of hyoscyamus (0.2%) in water. The formula calls for cannabis but this is filtered out.

USES: Similar in composition to the widely advertised nostrum Bromidia and equally irrational and objectionable.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=*Chloroformum (Chlorof.), Chloroform, U.S.P.=--CHCl{3}.

A clear, colorless liquid, with an ethereal odor and a burning, sweet taste. Slightly soluble (1:210) in water and miscible with alcohol, ether, petroleum benzin or fixed or volatile oils. Decomposed by alkalies.

ACTION AND USES: General anesthetic, administered by inhalation. Locally, a penetrating and fairly powerful irritant. Frequently used in the form of liniments. Taken by mouth in small doses, carminative, anodyne and antiseptic. Larger doses are anthelmintic but dangerous. A direct cardiac depressant.

DOSAGE: 0.3 Cc. or 5 minims (U.S.P.), diluted.

_*Aqua Chloroformi (Aq. Chlorof.), Chloroform Water, U.S.P._--A saturated solution of chloroform in water.

DOSAGE: 15 Cc. or 4 fluidrachms (U.S.P.).

_*Linimentum Chloroformi (Lin. Chlorof.), Chloroform Liniment, U.S.P._--A mixture of chloroform (30%) and soap liniment. Fairly active counterirritant.

_Mistura Chloroformi et Morphinae Composita (Mist. Chlorof. et Morph. Co.), Compound Mixture of Chloroform and Morphine, N.F._ (Mistura Chloroformi et Cannabis Indicae Composita, N.F. III, Chloroform Anodyne).--Morphine sulphate (0.25%), chloroform (12.5%), ether (3.25%), tincture of cannabis (18.5%), tincture of capsicum, oil of peppermint, glycerin, water and alcohol. Absolute alcohol content about 60 per cent.

USES: An evident imitation of the nostrum sold as chloranodyne, and equally irrational and objectionable.

DOSAGE: 2 Cc. or 30 minims (N.F.).

_Petroxolinum Chloroformi Camphoratum (Petrox. Chlorof. Camph.), Camphorated Chloroform Petroxolin, N.F._ (Camphor and Chloroform Petrox).--Chloroform (25%), camphor (25%) and liquid petroxolin.

_*Spiritus Chloroformi (Sp. Chlorof.), Spirit of Chloroform, U.S.P._--Chloroform (6%) in alcohol. Absolute alcohol content about 90 per cent.

DOSAGE: 2 Cc. or 30 minims (U.S.P.).

=Chlorum, Chlorine.=--Cl.

_Liquor Chlori Compositus (Liq. Chlor. Co.), Compound Solution of Chlorine, N.F._ (Chlorine Water).--A solution containing chlorine, oxides of chlorine and hydrochloric acid made by treating potassium chlorate with hydrochloric acid and dissolving the gases produced in water.

USES: Antiseptic.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=Chondrus (Chondrus), Chondrus, U.S.P.= (Irish Moss, Carrageen).--Plant.

ACTION AND USES: Demulcent and lubricant, possessing no advantages over other gums, acacia, for instance.

_Gelatinum Chondri (Gelat. Chondr.), Chondrus Gelatin, N.F._ (Irish Moss Gelatin).--Obtained by extraction with hot water and evaporation to semifluid consistency.

_Mucilago Chondri (Mucil. Chondr.), Mucilage of Chondrus, N.F._ (Mucilage of Irish Moss).--Chondrus (3%) in water.

=*Chromii Trioxidum (Chrom. Triox.), Chromium Trioxide, U.S.P.= ("Chromic Acid," Chromic Anhydride).--CrO{3}.

Dark purplish-red, odorless, deliquescent crystals. Very soluble in water (1:0.6). Decomposes, sometimes with dangerous violence, when brought into contact with organic solvents like alcohol and glycerin. Incompatible with most organic substances.

ACTION AND USES: A powerful oxidizing agent and caustic. Its action is somewhat difficult to control.

=*Chrysarobinum (Chrysarob.), Chrysarobin, U.S.P.=--Neutral principles from Goa powder.

Brownish to orange-yellow, tasteless, odorless powder, irritating to the mucous membrane. Slightly soluble in alcohol (1:385), soluble in chloroform (1:12.5) and very slightly soluble in water.

ACTION AND USES: Antiseptic and antiparasitic; a powerful irritant to the skin, used chiefly in the treatment of psoriasis, trichophytosis and alopecia areata.

_*Unguentum Chrysarobini (Ung. Chrysarobin.), Chrysarobin Ointment, U.S.P._--Chrysarobin (6%) in benzoinated lard.

=Cimicifuga (Cimicif.), Cimicifuga, U.S.P.= (Black Snake-root, Black Cohosh, Macrotys).--A rhizome.

ACTION AND USES: One of the class of "domestic medicines" that were tried for a great variety of conditions (used as "stomachic, antispasmodic, aphrodisiac, diaphoretic, diuretic and expectorant"), but which have not been found to possess definite value.

DOSAGE: 1 Gm. or 15 grains (U.S.P.).

_Extractum Cimicifugae (Ext. Cimicif.), Extract of Cimicifuga, U.S.P._ (Powdered Extract of Cimicifuga).--One Gm. extract represents 4 Gm. cimicifuga.

DOSAGE: 0.25 Gm. or 4 grains (U.S.P.).

_Fluidextractum Cimicifuga (Fldext. Cimicif.), Fluidextract of Cimicifuga, U.S.P._ (Fluidextract of Black Cohosh, Fluidextract of Black Snakeroot).--Cimicifuga (100%). Absolute alcohol content about 80 per cent.

DOSAGE: 1 Cc. or 15 minims (U.S.P.).

_Syrupus Cimicifugae Compositus (Syr. Cimicif. Co.), Compound Syrup of Cimicifuga, N.F._ (Syrupus Actaeae Compositus, N.F. III, Compound Syrup of Actaea).--Fluidextract of cimicifuga (4%), fluidextract of senega (2%), fluidextract of ipecac (1%), fluidextract of glycyrrhiza, wild cherry, sugar and water. Absolute alcohol content about 5 per cent.

USES: Complex expectorant.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

_Tinctura Cimicifugae (Tr. Cimicif.), Tincture of Cimicifuga, N.F._--Cimicifuga (20%) in alcohol. Absolute alcohol content about 90 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=*Cinchona (Cinch.), Cinchona, U.S.P.= (Yellow Cinchona, Calisaya Bark, Yellow Peruvian Bark).--Yields not less than 5 per cent. of alkaloids.

ACTION AND USES: Astringent bitter tonic.

DOSAGE: 1 Gm. or 15 grains (U.S.P.).

_Elixir Cinchonae Alkaloidorum and Elixir Cinchonae Alkaloidorum et Hypophosphitum._--See under =Quininae Sulphas=.

_Elixir Cinchonae Alkaloidorum et Ferri._--See under =Ferri Phosphas=.

_Elixir Cinchonae Alkaloidorum, Ferri, Bismuthi et Strychninae and Elixir Cinchonae Alkaloidorum, Ferri et Strychninae._--See under =Strychninae Sulphas=.

_Elixir Cinchonae Alkaloidorum, Ferri et Bismuthi._--See under =Bismuthi et Sodii Tartras=.

_Elixir Cinchonae Alkaloidorum, Ferri et Calcii Lactophosphatis._--See under =Calcii Lactophosphas=.

_Elixir Cinchonae Alkaloidorum, Ferri et Pepsini._--See under =Pepsinum=.

_Extractum Cinchonae (Ext. Cinchon.), Extract of Cinchona, N.F._--A hydroalcoholic extract diluted with glucose, yielding about 24 per cent. of cinchona alkaloids.

DOSAGE: 0.25 Gm. or 4 grains (N.F.).

_Fluidextractum Cinchonae (Fldext. Cinchon.), Fluidextract of Cinchona, U.S.P._--Cinchona (100%) yielding about 4.5 per cent. of alkaloids. Absolute alcohol content about 65 per cent.

DOSAGE: 1 Cc. or 15 minims (U.S.P.).

_Fluidextractum Cinchonae Aquosum (Fldext. Cinchon. Aq.), Aqueous Fluidextract of Cinchona, N.F._--Cinchona (100%), yielding about 5 per cent. of alkaloids. Absolute alcohol content about 12 per cent.

DOSAGE: 1 Cc. or 15 minims (N.F.).

_Infusum Cinchonae (Inf. Cinchon.), Infusion of Cinchona, N.F._--Cinchona (6%), aromatic sulphuric acid (1%) and water.

DOSAGE: 50 Cc. or 12 fluidrachms (N.F.).

_*Tinctura Cinchonae (Tr. Cinch.), Tincture of Cinchona, U.S.P._--Cinchona (20%), yielding about 0.9 per cent. of alkaloids; in alcohol, glycerin and water. Absolute alcohol content about 63 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (U.S.P.).

=Cinchona Rubra (Cinch. Rub.), Red Cinchona, U.S.P.= (Red Peruvian Bark).--Yields not less than 5 per cent. of alkaloids.

ACTION AND USES: Identical with those of cinchona. Used as ingredient of the compound tincture of cinchona.

_*Tinctura Cinchonae Composita (Tr. Cinch. Co.), Compound Tincture of Cinchona, U.S.P._--Red cinchona (10%), yielding about 0.45 per cent. of cinchona alkaloids, serpentaria (2%) and bitter orange peel, in glycerin, alcohol and water. Absolute alcohol content about 64 per cent.

USES: Aromatic astringent bitter, of high alcoholic content; superfluous.

DOSAGE: 4 Cc. or 1 fluidrachm (U.S.P.).

=Cinchonidinae Sulphas (Cinchonid. Sulph.), Cinchonidine Sulphate, U.S.P.=--The sulphate of the alkaloid cinchonidine, obtained from cinchona bark.

White, glistening, odorless needles with a very bitter taste. Soluble in water (1:65) and in alcohol (1:90).

ACTION AND USES: Formerly used as a cheap substitute for quinine sulphate, over which it possesses no advantage, being less efficient and more convulsant.

DOSAGE: 0.15 Gm. or 2-1/2 grains (U.S.P.).

=Cinchoninae Sulphas (Cinchonin. Sulph.), Cinchonine Sulphate, U.S.P.=--The sulphate of the alkaloid cinchonine, obtained from cinchona bark.

White, lustrous, odorless crystals with a very bitter taste. Soluble in water (1:60) and in alcohol (1:12.5).

ACTION AND USES: Similar to those of cinchonidine sulphate.

DOSAGE: 0.15 Gm. or 2-1/2 grains (U.S.P.).

=*Cinnamomum Saigonicum (Cinnam. Saigon.), Saigon Cinnamon, U.S.P.=--A bark.

ACTION AND USES: Carminative, antiseptic, somewhat astringent, occasionally administered in diarrhea.

DOSAGE: 0.25 Gm. or 4 grains (U.S.P.), in powder.

_Fluidextractum Aromaticum (Fldext. Aromat.), Aromatic Fluidextract, U.S.P._--Aromatic powder (100%), extracted with alcohol. Absolute alcohol content about 80 per cent.

DOSAGE: 1 Cc. or 15 minims (U.S.P.).

_Pulvis Aromaticus (Pulv. Arom.), Aromatic Powder, U.S.P._--Saigon cinnamon, Jamaica ginger, cardamom seed and nutmeg.

USES: Carminative.

DOSAGE: 1 Gm. or 15 grains (U.S.P.).

_Pulvis Cretae Aromaticus (Pulv. Cret. Arom.), Aromatic Powder of Chalk, N.F._--Saigon cinnamon, nutmeg, clove, cardamom seed, prepared chalk and sugar.

USES: Antidiarrheic.

DOSAGE: 2 Gm. or 30 grains (N.F.).

_Syrupus Cinnamomi (Syr. Cinnam.), Syrup of Cinnamon, N.F._--Saigon cinnamon, alcohol and syrup.

USES: Flavoring vehicle.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

_Tinctura Aromatica (Tr. Arom.), Aromatic Tincture, N.F._--Saigon cinnamon, Jamaica ginger, galangal, clove, cardamom seed, extracted with a mixture of alcohol and water. Absolute alcohol content about 63 per cent.

USES: Aromatic carminative, complex and without special advantage over other carminatives, as, for instance, tincture of cardamom.

DOSAGE: 2 Cc. or 30 minims (N.F.).

_Tinctura Cinnamomi (Tr. Cinnam.), Tincture of Cinnamon, U.S.P._--Saigon cinnamon in alcohol, glycerin and water. Absolute alcohol content about 63 per cent.

DOSAGE: 2 Cc. or 30 minims (U.S.P.).

=Cinnamomum Zeylanicum (Cinnam. Zeylan.), Ceylon Cinnamon, U.S.P.=--A bark.

ACTION AND USES: Same as those of Saigon cinnamon.

DOSAGE: 0.25 Gm. or 4 grains (U.S.P.)

=*Cocaina (Cocain.), Cocaine, U.S.P.=--An alkaloid obtained from coca leaves.

Large colorless prisms or a white powder; odorless. Slightly soluble in water (1:600) and freely soluble in alcohol (1:6.5) and in chloroform (1:0.7).

ACTION AND USES: A local anesthetic, paralyzing the peripheral sensory nerves and also contracting the blood vessels. Acute systemic poisoning is often caused by its local use on mucous membranes. Stimulant to the central nervous system, but such use is inadvisable because of danger of habit-formation.

DOSAGE: 0.015 Gm. or 1/4 grain (U.S.P.).

_Oleatum Cocainae (Oleat. Cocain.), Oleate of Cocaine, N.F._--Cocaine (5%) in alcohol, oleic acid and olive oil.

=*Cocainae Hydrochloridum (Cocain. Hydrochl.), Cocaine Hydrochloride, U.S.P.= (Cocaine Chloride, Cocainum Hydrochloricum, P.I.).

Colorless crystals, flaky leaflets or a white powder; odorless. Freely soluble in water (1:0.4) and in alcohol (1:3.2), and soluble in chloroform (1:12.5). Incompatible with borax, mercuric chloride, alkalies and alkali carbonates, phenol, tannic acid, mercuric oxide, and soluble silver salts.

ACTION AND USES: Local anesthetic.

DOSAGE: 0.015 Gm. or 1/4 grain (U.S.P.). For local anesthesia in 0.2 to 1.0 per cent. solution when used hypodermatically, and in 1 to 4 per cent. solution when applied to mucous membranes.

=Cocculus Indicus (Coccul. Ind.), Cocculus Indicus, N.F.= (Fish Berry, Indian Berry).--A fruit.

ACTION AND USES: Source of picrotoxin. An alcoholic extract has been used for destroying pediculi.

_Tinctura Cocculi Indici (Tr. Coccul. Ind.), Tincture of Cocculus Indicus, N.F._--Cocculus indicus (10%) in diluted alcohol. Absolute alcohol content about 45 per cent.

=Coccus (Coccus), Cochineal, U.S.P.=--A dried insect.

ACTION AND USES: Coloring agent.

_Liquor Cocci (Liq. Cocci), Cochineal Color, N.F._--A glycerin-alcohol-water solution of cochineal.

=Cocillana (Cocillan.), Cocillana, N.F.=--A bark.

ACTION AND USES: Nauseant expectorant, similar to but without advantage over ipecac. The proprietary syrup contains heroin.

DOSAGE: 1 Gm. or 15 grains (N.F.).

_Fluidextractum Cocillanae (Fldext. Cocillan.), Fluidextract of Cocillana, N.F._--Cocillana (100%). Absolute alcohol content about 60 per cent.

DOSAGE: 1 Cc. or 15 minims (N.F.).

=*Codeina (Codein.), Codeine, U.S.P.= (Methylmorphine).--An alkaloid obtained from opium, or prepared from morphine by methylation.

Colorless, translucent prisms or a white powder; odorless. Slightly soluble in water (1:120) and freely soluble in alcohol (1:2) and in chloroform (1:0.5).

ACTION AND USES: Analgesic, hypnotic and sedative. It is perhaps the best modification of morphine for use in coughs. As compared with morphine it is less constipating and less apt to induce a drug habit. The phosphate and sulphate are preferred for hypodermic use.

DOSAGE: 0.03 Gm. or 1/2 grain (U.S.P.).

_Elixir Terpini Hydratis et Codeinae (Elix. Terpin. Hyd. et Codein.), Elixir of Terpin Hydrate and Codeine, N.F._--Codeine (0.2%) and elixir of terpin hydrate. Absolute alcohol content about 42 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.). This dose contains about 0.008 Gm. or 1/8 grain of codeine, and about 0.07 Gm. or 1-1/6 grains of terpin hydrate.

=*Codeinae Phosphas (Codein. Phos.), Codeine Phosphate, U.S.P.=

White, odorless, efflorescent powder. Freely soluble in water (1:2.3) and slightly soluble in alcohol (1:325).

ACTION AND USES: Same as those of codeine; preferred for hypodermic use.

DOSAGE: 0.03 Gm. or 1/2 grain (U.S.P.).

=*Codeinae Sulphas (Codein. Sulph.), Codeine Sulphate, U.S.P.=

White, odorless, efflorescent crystals or powder. Soluble in water (1:30) and very slightly soluble in alcohol (1:1280).

ACTION AND USES: Same as those of codeine. Preferred for hypodermic injections.

DOSAGE: 0.03 Gm. or 1/2 grain (U.S.P.).

_Syrupus Codeinae (Syr. Codein.), Syrup of Codeine, N.F._--Codeine sulphate (0.2%) and syrup.

USES: Superfluous.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.)

=Coffea Tosta (Coff. Tost.), Coffee, N.F.= (Roasted Coffee).

ACTION AND USES: Beverage and flavor.

_Fluidextractum Coffeae (Fldext. Coff.), Fluidextract of Coffee, N.F._ (Fluidextractum Coffeae Tostae, N.F. III).--Coffee (100%). Absolute alcohol content about 20 per cent.

DOSAGE: 2 Cc. or 30 minims (N.F.).

=Colchici Cormus (Colch. Corm.), Colchicum Corm, U.S.P.= (Colchicum Root).--Yields not less than 0.35 per cent. of colchicine.

ACTION AND USES: Said to be antineuralgic and analgesic; frequently used in the treatment of acute gouty attacks and to some extent to ward off such attacks. Full doses produce watery stools and abdominal pains.

DOSAGE: 0.25 Gm. or 4 grains (U.S.P.), in pills; or preferably as the tincture.

_Extractum Colchici Cormi (Ext. Colch. Corm.), Extract of Colchicum Corm, U.S.P._ (Powdered Extract of Colchicum Corm).--One Gm. extract represents 4 Gm. colchicum corm and yields about 1.4 per cent. of colchicine.

DOSAGE: 0.06 Gm. or 1 grain (U.S.P.).

_Fluidextractum Colchici Cormi (Fldext. Colch. Corm.), Fluidextract of Colchicum Corm, N.F._--Colchicum corm (100%), yielding about 0.35 per cent. of colchicine. Absolute alcohol content about 55 per cent.

DOSAGE: 0.2 Cc. or 3 minims (N.F.).

_Vinum Colchici Cormi (Vin. Colchic. Corm.), Wine of Colchicum Corm, N.F._--Colchicum corm (40%) yielding about 0.14 per cent. of colchicine, in alcohol and sherry wine. Absolute alcohol content about 30 per cent.

DOSAGE: 0.6 Cc. or 10 minims (N.F.).

=*Colchici Semen (Colch. Sem.), Colchicum Seed, U.S.P.= (Colchici Semen P.I.).--Yields not less than 0.45 per cent. of colchicine.

ACTION AND USES: Same as those of colchicum corm.

DOSAGE: 0.2 Gm. or 3 grains (U.S.P.).

_Fluidextractum Colchici Seminis (Fldext. Colch. Sem.), Fluidextract of Colchicum Seed, U.S.P._--Colchicum seed (100%), yielding about 0.4 per cent. of colchicine. Absolute alcohol content about 55 per cent.

DOSAGE: 0.2 Cc. or 3 minims (U.S.P.).

_*Tinctura Colchici Seminis (Tr. Colch. Sem.), Tincture of Colchicum Seed, U.S.P._ (Colchici Tinctura P.I.).--Colchicum seed (10%), yielding about 0.04 per cent. of colchicine; in alcohol and water. Absolute alcohol content about 56 per cent.

DOSAGE: 2 Cc. or 30 minims (U.S.P.).

_Vinum Colchici Seminis (Vin. Colch. Sem.), Wine of Colchicum Seed, N.F._--Fluidextract of colchicum seed (10%), yielding about 0.04 per cent. of colchicine; in alcohol and sherry wine. Absolute alcohol content about 35 per cent.

DOSAGE: 2 Cc. or 30 minims (N.F.).

=Colchicina (Colchicina), Colchicine, U.S.P.=--An alkaloid obtained from colchicum.

Pale yellow, odorless scales or powder. Freely soluble in alcohol, soluble in water (1:22) and slightly soluble in ether (1:220).

ACTION AND USES: Same as those of colchicum corm.

DOSAGE: 0.5 mg. or 1/120 grain.

=COLLODIA, COLLODIONS.=--Collodions are solutions of pyroxylin or soluble gun cotton with medicinal agents, for external application. For the official collodions see under the names of the principal ingredients. In particular, for Collodium, see under =Pyroxylin=; for Collodium Flexible, under =Oleum Ricini=; and for Collodium Stypticum, under =Acidum Tannicum=.

=*Colocynthis (Colocyn.), Colocynth, U.S.P.= (Colocynth Pulp, Bitter Apple, Colocynth Apple).

ACTION AND USES: A powerful irritant hydragogue cathartic. Because of its drastic nature it is rarely used alone. The various compound pills listed below are needlessly complex and therefore irrational. Because of their irritant character, they are especially unsuited for continued use.

DOSAGE: 0.06 Gm. or 1 grain.

_*Extractum Colocynthidis (Ext. Colocynth.), Extract of Colocynth, U.S.P._ (Powdered Extract of Colocynth).--One Gm. of extract represents 4 Gm. of colocynth.

DOSAGE: 0.015 Gm. or 1/4 grain (U.S.P.).