Drug Plants Under Cultivation

Part 4

Chapter 44,294 wordsPublic domain

If the trees are pruned properly, a crop of bark may be harvested each year without killing the whole tree, as is done in collecting the bark from wild trees. At the time of transplanting, the trees are cut back to a straight stem about a foot high, from which all except the four uppermost buds are removed. The branches which afterwards develop from these buds are later deprived of their lower side shoots, thus causing the tree to grow a head of four long, stout branches instead of a single straight trunk. When the trees are large enough to yield a crop of bark, the longest of the four branches is cut off early in the spring flush with the trunk and a new branch is allowed to grow in its place. This process may be repeated yearly, removing only the largest branches of each tree in any one season.

The bark on the cut-off branches is divided with a sharp knife into lengthwise strips of about an inch or two in width, which may be readily pulled off. It is then dried carefully at a low temperature in the shade and broken into small pieces to facilitate packing and handling.

The price paid to collectors for cascara bark, which before the war usually varied from 1 to 4 cents a pound, in June, 1920, was about 10 cents a pound. So long as a supply of the wild bark continues to be available it is doubtful whether cascara can be cultivated at a profit.

CASTOR BEANS.

The castor-oil plant or Palma Christi (_Ricinus communis_) is a robust perennial in tropical countries which becomes an annual in regions subject to frost. The seeds of this plant, called "castor beans" or "mole beans," yield the castor oil of commerce. Between 1860 and 1900, the castor bean was an important crop in certain sections of Oklahoma, Kansas, Missouri, and Illinois, but during recent years its culture has been practically abandoned in favor of crops which are easier to handle and more profitable.

For the commercial production of castor beans a warm climate and long growing season are necessary. If planted much farther north than St. Louis, Mo., or Washington, D. C, the crop is very likely to be caught by frost. In general, any fertile soil which produces good crops of cotton or corn is suitable for castor beans, but a very fertile soil favors the growth of the plant at the expense of seed production and early maturity. The land is prepared in much the same manner as for cotton or corn; that is, plowed, disked, and harrowed level before planting, which may be done by hand or with a corn planter with specially prepared plates. The seed should be planted early in the spring, as soon as the soil is warm but still moderately moist. The time of planting varies according to locality, but in general corresponds to that of cotton.

The seed is planted in hills at a depth of 1 to 2 inches. Toward the north, the rows are usually made 4 feet apart and the hills spaced 3 feet apart in the row. Farther south the rows should usually be made about 6 to 8 feet apart. On very light land the hills may be 4 feet apart in the row; on heavier land, 6 to 8 feet apart. As a general rule three seeds are planted to the hill, and not less than two should be planted. One bushel of medium-sized seed should plant from 5 to 6 acres. When the plants are from 4 to 6 inches tall, the weaker ones should be removed, leaving one plant in a hill.

The crop is cultivated similar to corn until the plants are large enough to shade the ground. In case the field becomes foul with weeds and grass, some hoeing may be necessary, but practically all the cultivation required can be done with a horse-drawn weeder. Some varieties in which the beans pop out when the hull is fully ripe are known locally as "poppers," and after the beans begin to ripen, the field must be gone over every few days and the ripe beans collected in order to avoid loss. Other varieties tend to retain the beans in the hull after they are ripe. The climate affects the popping of the beans, and a variety which shatters badly in one region may shatter very little when grown in another.

In harvesting, a common method is to cut off the spikes with a knife and collect them in large sacks. They are then hauled to a shelter of some kind and allowed to dry until the pods will crush easily. Various methods are used in thrashing castor beans. If the variety grown is one which "pops" or drops its seeds when they are ripe, the spikes are sometimes piled on a hard ground or plank floor fully exposed to the sun and furnished with sides of boards or cloth 6 to 8 feet high to catch the beans as they pop out. In some varieties mere drying does not cause the pods to open, and specially constructed machines have been used to remove the beans from the pods. After the beans have been thrashed or popped out, a fanning mill is used to separate the hulls, chaff, and dirt from the beans, which are then sacked and stored for market.

The yield varies greatly and will depend much upon cultural conditions, the season, the variety grown, and the care exercised in harvesting and thrashing the seeds. In Oklahoma the average yield of the popping varieties is said to be 8 to 10 bushels per acre. Yields up to 25 bushels per acre have been reported for favorable conditions.

For some years prior to the war the farm price for castor beans was about $1 a bushel. Early in the war the increased demand for castor oil caused a sharp advance in the price of the beans, which has gradually declined. In June, 1920, the wholesale market quotation was about $3 a bushel. The normal market requirement in the United States for castor beans is about 1,000,000 bushels annually, but during the last year of the war nearly 3,000,000 bushels were imported.

In the United States castor beans are used in quantity only by manufacturers of castor oil. In general, the equipment and operation of a castor-oil mill resembles that of a cottonseed-oil mill or linseed-oil mill, but special and expensive equipment is necessary for the proper extraction of the oil from castor beans. The best grade of oil is obtained from the beans by hydraulic pressure. An additional quantity of oil of lower grade is obtained by treating the press cake with naphtha or some other volatile solvent. The pomace resulting from the second extraction is used as a fertilizer for tobacco, corn, and other crops, but because of a poisonous principle can not be used for cattle feeding unless specially treated.

Owing to the heavy outlay required for the necessary machinery and the high cost of manufacture on a small scale, it has not been found profitable for the growers of castor beans to undertake the extraction of the oil.

The castor-oil plant is not known to be poisonous, and although the leaves are not relished by farm animals they are said to be used as fodder for cattle in India. Castor beans, however, contain a poisonous principle, and though harmless when handled, may cause serious if not fatal effects when eaten, especially in the case of small children. Care should be taken to prevent these beans from being accidentally mixed with the grain fed to animals, since many cases have been reported in which the death of horses has been due to eating feed in which they have become mixed.

CATNIP.

Catnip (_Nepeta cataria_) is a European perennial plant of the mint family, which frequently occurs in this country as a weed in gardens and about dwellings. It has long had a popular use as a domestic remedy. Both leaves and flowering tops find some demand in the crude-drug trade.

Catnip does well on almost any good soil, but thrives best on a well-drained and moderately rich garden loam. However, a more fragrant and attractive herb can be grown in sandy situations than in heavy soils. The plant may be propagated from seeds or by root division. The seed may be sown in rows either late in the fall or in early spring and covered lightly. Fall-sown seed usually gives a more even stand and a heavier growth of herb. When the plants have reached a height of 4 to 5 inches they should be thinned to stand from 12 to 16 inches apart in the rows. In some localities the field sowing of seed does not give good results, in which case plants may be started in a coldframe and later transplanted to the field. Shallow cultivation will favor a vigorous growth of the herb.

The flowering tops are harvested when the plants are in full bloom and are dried in the shade to preserve their green color. In case the herb is grown in large quantity, it may be cut with a mowing machine, the cutter bar of which should be set high. The plants should lie in the swath until partially dry, and the curing may then be finished either in small cocks in the field or in the barn, care being taken to preserve the natural green color as far as possible.

Returns from experimental areas indicate that a yield of about 2,000 pounds of dried flowering tops per acre may be expected under good conditions. The herb must be carefully sorted and all the large or coarse stems removed, after which it may be made up for the market in bales of 100 to 300 pounds each. Prewar prices to collectors ranged from 2 to 4 cents a pound. The prices in June, 1920, for the herb were 5 cents; for the leaves, 10 cents; and for the leaves and flowers, 14 cents a pound.

CHAMOMILE. (See CAMOMILE.)

CONIUM.

Conium, or poison hemlock (_Conium maculatum_), is a large, poisonous European biennial plant of the parsley family, naturalized in the Northeastern States and in California. The full-grown but unripe seeds (fruits) and the leaves are used medicinally.

Conium is easily grown, and has been found to thrive in both comparatively moist clay soil and in dry sandy loam. In rich, moist land it may easily become a troublesome weed. Conium grows readily from seed, which may be sown either in the fall or early in the spring in drills 2 or more feet apart. As soon as the seedlings can be distinguished in the row, cultivation similar to that given ordinary garden crops is begun. The plants usually blossom in the second year, and when the oldest seeds are full grown but still green in color the plants are harvested and the seed at once thrashed out and dried with the least possible exposure to the light. The small and undeveloped seed should be screened out and rejected and the good seed stored in containers that will exclude light and air. The leaves are collected when the plant is in flower, quickly dried in the sun, and stored in the same manner as the seed.

Estimated yields at the rate of 600 to 800 pounds of seed per acre have been obtained, but the yield is very uncertain, since the flowering plants are especially subject to the attacks of insects which destroy the crop of seed. The prewar prices as quoted in the wholesale drug markets ranged from 5 to 10 cents a pound for the seed and 5 to 6 cents for the leaves. The prices in June, 1920, for the seed were 35 to 36 cents, and for the leaves 25 to 26 cents a pound.

CORIANDER.

Coriander (_Coriandrum sativum_) is an Old World annual of the parsley family. For years the plant has been cultivated in gardens in the United States, and it is now reported as growing wild in many places. The aromatic seeds and the oil distilled from them have long been used medicinally. Both the seed and the oil are also used for flavoring confectionery and cordials and as a condiment in bread and cake.

Coriander grows well on almost any good soil, but thrives best on deep and fertile garden loam. The soil should be well prepared before planting, which should be done moderately early in the spring. For field cultivation the seed is sown in rows 3 feet apart, but if the cultivation is done by hand the distance between the rows may be reduced to 18 inches. The seed should be sown thickly in order to insure a good stand. When well up, the plants are thinned to stand 4 or 5 inches apart in the row. Cultivation should continue until the plants flower, which will be about two months from the time of planting.

When most of the seeds are ripe the plants are cut with a scythe or mower, preferably early in the morning while moist with dew, in order to avoid shattering the seed. The plants are partially cured in small cocks in the field, the drying being finished in a barn loft or under other suitable shelter, after which the seeds are thrashed out and cleaned.

The yield of seed is quite variable, but returns from experimental areas indicate that from 500 to 800 pounds per acre may be expected. Five hundred pounds of seed will usually yield from 1 to 5 pounds of oil, according to the localities where grown. The annual importation of coriander seed is about 1,400,000 pounds. The prewar price of the seed was about 3 cents a pound; in June, 1920, 3 to 4 cents. The wholesale price of the oil of coriander, which was $5 to $7 a pound before the war, in June, 1920, ranged from $42 to $45 a pound.

DANDELION.

Dandelion (_Taraxacum officinale_) is a well-known and troublesome perennial weed, occurring abundantly almost everywhere in this country except in the Southern States. It is frequently cultivated in market gardens for the leaves, which are used for greens or salads, but the root alone is used in medicine.

This plant will grow well in any good soil and has been successfully cultivated in the South, but in the colder parts of the country it may require slight mulching during the winter if the roots tend to heave out of the soil. The seeds, which are sown in the spring, are drilled in rows 18 inches apart and covered one-half inch deep. About 3 pounds of seeds should sow an acre. The seedlings are thinned to stand a foot apart in the row, and the crop should be well cultivated and kept free from weeds.

The roots are dug in the fall of the second season after planting the seed. They should be washed and may be dried whole, or, to facilitate handling and drying, they may be cut into pierces 3 to 6 inches long and the larger, portions sliced. Under favorable conditions, yields at the rate of 1,000 to 1,500 pounds of dry roots per acre have been obtained from second-year plants. The prices usually offered collectors for the dry root before the war ranged from 4 to 10 cents a pound. The price in June, 1920, was about 16 cents. The quantity annually imported into this country varies from year to year, but averages about 40 tons.

A serious disadvantage attending the cultivation of this crop is the danger of seeding adjacent land with a very undesirable weed.

DIGITALIS.

Digitalis, or foxglove (_Digitalis purpurea_), is a fairly hardy European perennial, which has long been grown in flower gardens in this country as an ornamental plant. The leaves are used in medicine, those from plants of the second year's growth being required for the official drug.

Digitalis thrives in ordinary well-drained garden soils of open texture and reasonable fertility. Sowing the seed directly in the field occasionally gives good results, but is so often unsuccessful that it can not be recommended. The seeds are exceedingly small and do not germinate well except under the most favorable conditions. They should be mixed with sand, to insure even distribution in seeding, and sown as early as February in seed pans or flats in the greenhouses or in well-protected frames. When danger of frost is past the plants should be hardened off and transplanted to the field, where they may be set about a foot apart in rows spaced conveniently for cultivation.

The plants do not flower until the second year, and it is necessary to cultivate them frequently during the growing seasons of both the first and second year. In localities where the cold weather is severe it may be desirable to protect the plants during the first winter with a light mulch of straw or coarse farmyard manure.

The plants usually flower in June of the second year, and the leaves may then be collected. They are carefully dried in the shade and should be stored in such a manner that they will not be exposed to light and moisture. The results of experiments indicate that yields of 450 to 600 pounds of dry leaves per acre may be obtained under favorable conditions. In considering digitalis culture it should be borne in mind that the crop occupies the soil for the greater part of two seasons and demands even closer attention than many truck or garden crops.

In 1919 small areas of cultivated digitalis, ranging from one-half to 1 acre in extent, were harvested in Pennsylvania, South Carolina, Washington, California, and some other States. Several tons of digitalis leaves were also collected from plants of wild growth in the general region of the Coast Range of mountains on the Pacific coast. Digitalis is of great medicinal importance, but on account of its potency is administered in very small quantities; consequently, a few thousand pounds is sufficient to meet the annual market requirements. Before the war the price for digitalis leaves averaged about 15 cents a pound; in June, 1920, it was about 35 cents a pound.

DILL.

Dill (_Anethum graveolens_) is an Old World annual or biennial herb of the parsley family. Although it is a native of southern Europe, it is hardy plant and may be grown in a much cooler climate if given a warm situation and a well-drained soil. The leaves are used for seasoning, and the seeds (fruits), which are greatly valued for flavoring pickles, are used as a condiment and occasionally in medicine. A volatile oil distilled from the seeds is used chiefly for perfuming soap.

Dill is preferably grown as an annual plant, in which case the seed should be sown about one-half inch deep very early in the spring in drills a foot apart. A half ounce of seed is sufficient to sow 150 feet of drill, and at this rate a pound should sow an acre. When sown in the field the rows may be 15 to 18 inches apart, and the seedlings should be thinned to stand about a foot apart in the row. The most favorable soil is a well-prepared loam, but the plants grow well in any good garden soil. Frequent cultivation and freedom from weeds are essential for good results.

Early in the fall, as soon as some of the older seeds are ripe, the plants are mowed and built up; into small cocks in the field, or, if sufficiently dry, the seeds may be thrashed out at once. In very dry weather it is preferable to mow the plants early in the morning while they are moist with dew, in order to avoid shattering the seed. In case the seed is very ripe, it is well to cut the plants high and to place the tops directly on large canvas sheets, in which they may be brought from the field. After thrashing, the seeds should be spread out in a thin layer and turned frequently until thoroughly dry, since they tend to become musty if closely stored before all the moisture has been removed.

The yield of dill seed is quite variable and is much influenced by climatic conditions. From 500 to 700 pounds of seed per acre is considered a good yield. The wholesale price in June, 1920, ranged from 8 to 11 cents a pound.

ECHINACEA.

Echinacea (_Brauneria angustifolia_, fig. 6) is a native perennial plant of the aster family found on the prairies of the Middle West, occurring most abundantly in Nebraska and Kansas. The roots of the plant are used medicinally.

This plant has been found to do well under, cultivation in moderately rich and well-drained loam. It grows fairly well from seeds, which may be collected when ripe and kept dry until ready for use. Plants should be started in a well-prepared seed bed by sowing the seeds thinly in drills about 8 inches apart. The plants develop slowly and may be left in the seed bed for two years and then transplanted to the field in the spring and set about 18 inches apart In rows. Thorough cultivation is essential for the best results. The roots do not reach a marketable size under three or four years from the time of sowing the seed. They are harvested in the fall, freed from any adhering soil, and dried either in the open air or by means of low artificial heat.

Echinacea has not been cultivated on a scale large enough to give satisfactory data on the probable yield. The prewar wholesale price ranged from 22 to 60 cents a pound; in June, 1920, it was 60 to 65 cents a pound.

ELECAMPANE.

Elecampane (_Inula helenium_) Is a European perennial plant of the aster family, now growing wild along roadsides and in fields throughout the northeastern part of the United States. The root is used in medicine.

Elecampane will grow in almost any soil, but thrives best in deep clay loam well supplied with moisture. The ground on which this plant is to be grown should be deeply plowed and thoroughly prepared before planting. It is preferable to use divisions of old roots for propagation, and these should be set in the fall about 18 inches apart in rows 3 feet apart. Plants may also be grown from seeds, which may be sown in the spring in seeds beds and the seedlings transplanted later to the field and set in the same manner as the root divisions. Plants grown from seed do not flower the first year. Cultivation should be sufficient to keep the soil in good condition and free from weeds.

The roots are dug in the fall of the second year, thoroughly cleaned, sliced, and dried in the shade. The available data on yield indicate that a ton or more of dry root per acre may be expected. The price to producers usually ranges from 3 to 6 cents a pound. Upward of 50,000 pounds of elecampane root were annually imported into this country prior to the war.

FENNEL.

Fennel (_Foeniculum vulgare_) is an Old World perennial plant of the parsley family, occasionally cultivated as a garden herb in the United States. The aromatic seeds (fruits) are used in medicine and for flavoring. The oil distilled from the seeds is used in perfumery and for scenting soaps.

Fennel grows wild in mild climates in almost any good soil and thrives in rich, well-drained loams containing lime. It is propagated from seeds, which may be sown in the open as soon as the ground is ready for planting in the spring. The seed is sown thickly In drills 2 to 3 feet apart and covered lightly. From 4 to 5 pounds of seed should sow an acre. When well established the plants may be thinned to stand 12 to 15 inches apart in the row. Plants may also be started in a seed bed from seed sown either in drills 6 inches apart or broadcast. When the seedlings are three or four inches high they are transplanted to the field and set 12 to 15 inches apart in rows. The cultivation is the same as for ordinary garden crops.

Frequently, very little seed is formed the first year, but full crops may be expected for one or two succeeding years. The seed is gathered in the fall before it is fully ripe and may be harvested like anise or coriander. A yield of 600 to 800 pounds of seed, per acre may be expected. During recent years about 275,000 pounds of seed have been imported annually. Owing to the war, prices for the seed and oil have about doubled. The prices in June, 1920, for the seed were 11 to 12 cents a pound; for the oil, $2.75 to $3 a pound.

GENTIAN.

The common or yellow gentian (_Gentiana lutea_) is the only species recognized in American medicine, although the roots of several other species are found in the drug trade. The plant grows wild in the mountains of central and southern Europe, but it has proved very poorly adapted for cultivation in situations beyond its natural range. For its best development under cultivation, partial shade, similar to that required by ginseng and goldenseal, seems necessary. The plants are said to flower when about 6 years old; hence, several years must elapse after sowing the seed before the roots reach a marketable size. Apparently there have been no attempts to cultivate gentian commercially in this country. The prewar wholesale price of imported gentian root ranged from 4½ to 8 cents a pound. The price in June. 1920, was 12 to 13 cents a pound.