volume iv of our series, note 76.--ED.

[25] A sketch of the settlement of Marietta will be found in André Michaux’s _Travels_, volume iii of our series, note 16.--ED.

[26] For Belpré, see Cuming’s _Tour_, volume iv of our series, note 87.--ED.

[27] Letart Falls are at the northward turn of the river in the so-called “Pomeroy Bend” between Meigs County, Ohio, and Mason County, Kentucky. The rapids are of slight consequence, but were exaggerated into importance by some of the early travellers.--ED.

[28] For sketch of Gallipolis and the unfortunate French colony of which it was the centre, see F. A. Michaux’s _Travels_, in our volume iii, note 34.--ED.

[29] Point Pleasant is at the mouth of Great Kanawha River. For history of the site, see Croghan’s _Journals_, volume i of our series, note 101; also Bradbury’s _Travels_, in our volume v, note 156.--ED.

[30] A more particular account of these monuments is given in the latter part of this work.--NUTTALL.

[31] Portsmouth is situated at the mouth of the Scioto, on the east bank. On the west bank was the chief Shawnee village, in the days of rivalry between French and English fur-traders. Gist, exploring for the Ohio Company, was here in 1751. Two years later a flood drove the Indians across the river to the higher ground on which Portsmouth was afterwards built; but a part of them removed to the upper Scioto and the Little Miami, founding the Old and New Chillicothe towns. Portsmouth was the place of captivity of Mrs. Mary Ingles, in 1755; the site was abandoned by the Indians in 1758. The present town was platted (1803) by Henry Massie, on land bought by him in 1801. It was named for Portsmouth, Virginia.--ED.

[32] For the history of Maysville (formerly called Limestone), see André Michaux’s _Travels_, in our volume iii, note 23.--ED.

[33] Augusta is forty-two and a half miles above Cincinnati. It was formerly seat of justice of Bracken County, Kentucky, and is still, on account of its good harbor, an important point for shipping tobacco.--ED.

[34] For a sketch of the early history of Cincinnati, see Cuming’s _Tour_, in our volume iv, note 166.--ED.

[35] Nuttall mistook the name. Dr. Daniel Drake came to Cincinnati from Kentucky in 1800, at the age of fifteen, and clerked in a drug store while privately studying medicine. He was graduated from the medical school of Pennsylvania University, in 1816, and the next winter lectured at Transylvania University. The plan for a medical college, referred to in the text, was successfully carried out. The charter was obtained in December, 1818, the college being opened the following November, with twenty-five students. Drake was president. This was the beginning of the Ohio Medical College. In 1821, Drake secured from the legislature a grant which laid the foundation for the Cincinnati hospital. For many years he was the leader of his profession in Ohio and Kentucky, and was influential in numerous progressive movements. He died in 1852, a member of the faculty of the college founded in 1818–20. See biographical sketch by his son, prefixed to a collection of his letters, _Pioneer Life in Kentucky_ (Cincinnati, 1870).

Hugh Glenn, mentioned in the succeeding paragraph, soon afterward established a trading-post near the mouth of the Verdigris River, in what is now Indian Territory. He was one of the first to succeed in the Santa Fé overland trade.--ED.

[36] Lawrenceburgh is the seat of justice of Dearborn County, Indiana. The town was laid out in 1802 by Samuel C. Vance, United States surveyor at Cincinnati, who bought the site in 1801. He named the town for his wife, whose maiden name was Lawrence. The site is low, and subject to inundations.--ED.

[37] Founded in 1813.--ED.

[38] For an account of the founding of the Swiss settlements in Indiana, see Bradbury’s _Travels_, in our volume v, note 164.--ED.

[39] Madison, first settled about 1808, is the seat of justice of Jefferson County, Indiana.--ED.

[40] For description of the Falls of the Ohio and the early history of Louisville, see Croghan’s _Journals_, in our volume i, note 106. A company was chartered in 1818 to build a canal around the falls, but the work was not completed until December, 1830, under the direction of the Louisville and Portland Canal Company, organized in 1825. After 1845, the stock was gradually purchased by the United States, which eventually became entire owner.--ED.

[41] For sketch of Shippingsport, see Cuming’s _Tour_, in our volume iv, note 171.--ED.